Compare Stribild vs. Sustiva

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)

Prescription only
Treats HIV infection.

Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication and one of the first choices used to treat HIV infections.

Works with other medicines to treat HIV infection.

Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.

Upsides
  • First-choice treatment for HIV in patients with good kidney function.
  • One tablet contains four different HIV medications.
  • Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) is only taken once daily.
  • There are assistance programs available through the manufacturer of Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir) if you need help paying for high insurance copays.
  • If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
  • Only taken once daily.
  • Sustiva (efavirenz) is available in combination tablets.
  • Can be used in patients with mild to moderate kidney damage.
  • Can be used in children who are at least 3 months old.
Downsides
  • Can't be used in patients with kidney problems.
  • Can interact with many other drugs.
  • Not suggested for women who plan on becoming pregnant.
  • Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
  • Cannot be taken alone for treatment of HIV.
Used for
Dosage forms
  • Pill
  • Pill
Price
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$3158.78
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Lowest price near you
$1007.22
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Reviews
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Side effects
9possible side effects
  • Nausea
    16%
  • Diarrhea
    12%
  • Abnormal dreams
    9%
  • Headache
    7%
  • Fatigue
    4%
  • Rash
    4%
  • Dizziness
    3%
  • Insomnia
    3%
  • Flatulence
    2%
See more detailed side effects
8possible side effects
  • Skin rash
    16%
  • Diarrhea
    14%
  • Pain
    13%
  • Nausea
    10%
  • Dizziness
    9%
  • Itching
    9%
  • Fatigue
    8%
  • Headache
    8%
See more detailed side effects
Risks and warnings
  • Lactic acidosis | Enlarged, fatty liver

    Liver disease

    ...and 2 more risk factors

  • Cannot be used to treat Hepatitis B Virus (HBV)

    Hepatitis B Virus infection

  • Decreased bone mineral density

    History of bone fractures

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 1 more risk factors

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

  • Drug interactions

    Taking medicines that interact with Stribild (elvitegravir / cobicistat / emtricitabine / tenofovir)

See more detailed risks and warnings
  • Central nervous system (CNS) effects

    Starting Sustiva (efavirenz) for the first few weeks.

    ...and 1 more risk factors

  • Fat redistribution

    HIV treatment

  • Liver damage

    History of liver damage

    ...and 1 more risk factors

  • Immune reconstitution syndrome

    HIV

    ...and 3 more risk factors

  • Psychiatric effects

    History of mental illness

    ...and 1 more risk factors

  • Rash

    History of severe skin reactions

    ...and 1 more risk factors

See more detailed risks and warnings