Compare Sudafed vs. Nasonex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sudafed
(pseudoephedrine)

Nasonex
(mometasone)

Clears your sinuses. Sudafed (Pseudoephedrine) relieves stuffy nose, but it could keep you up at night. Don't forget your photo ID or you won't be able to buy it in the drugstore.Relieves allergy symptoms. Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.28Sudafed
Reviews for Sudafed
82%
of people (All ages) say Sudafed is worth it
45%
say it works well
6%
say it's a big hassle
1740 reviews
Have you used Sudafed (pseudoephedrine)?
Worth itNot sureNot worth it
Reviews for Nasonex
68%
+14% better vs. Sudafed
39%
+6% better vs. Sudafed
8%
+2% better vs. Sudafed
675 reviews
Have you used Nasonex (mometasone)?
Worth itNot sureNot worth it
Side effects
SudafedNasonex

We haven’t found good data for Sudafed side effects.

FDA side effect reports for Sudafed »
  • Headache 4%
  • Viral infection 3%
  • Sore throat 2%
  • Nosebleed 5%
  • Coughing 1%
  • Ear, nose, or throat infection 4%
  • Menstrual cramps 2%
  • Musculoskeletal pain 2%
  • Sinus inflammation 2%
  • Joint pain 4%
More Nasonex side effects »
How it works
SudafedNasonex
Sudafed (Pseudoephedrine) is a decongestant. It narrows blood vessels and reduces swelling in your nasal passages to make breathing easier.Nasonex (Mometasone) is a topical steroid. It works directly where it's applied to help reduce swelling and inflammation in your nose.
Type of medication
SudafedNasonex
Prescription or OTCPrescription only
Available as
SudafedNasonex
  • Pill
  • Extended release
  • Liquid
  • Nasal spray
Used for
SudafedNasonex
Risk factors for serious side effects
SudafedNasonex
  • History of high blood pressure
  • History of heart problems
  • Age 65 years or older
  • History of seizures
  • Women of childbearing age
Detailed Sudafed (pseudoephedrine) risks & warnings »
  • Long-term use
  • Surgery or trauma to the nose or sinuses
  • Exposure to immunizable diseases (chickenpox and measles)
Detailed Nasonex (mometasone) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Pain
SudafedNasonex
No pain related info.
  • Long-term use of Nasonex (Mometasone) can increase your chances of getting thrush in the nose and throat. Your doctor will check your nose and throat if you have to be on this medication for a long time. Also, tell your doctor if you notice pain in the nose and throat with redness and white patches.
Sleep
SudafedNasonex
  • It can affect the quality of your sleep, so you can't take it too close to going to bed.
No sleep related info.
Upsides and benefits
SudafedNasonex
  • One of the best over-the-counter options to clear stuffy nose and help you breathe better.
  • Clears nasal congestion better than other decongestants like phenylephrine.
  • Can be helpful in relieving congestion-related headaches and pressure in your ears.
  • Available in regular and extended release forms.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
Downsides and risks
SudafedNasonex
  • Pseudoephedrine (a decongestant) can make your heart race or make you feel anxious and restless.
  • It can affect the quality of your sleep, so you can't take it too close to going to bed.
  • Can raise blood pressure so check with your doctor before using it if you have high blood pressure or other heart conditions.
  • Sudafed (Pseudoephedrine) isn't as effective after using it for more than 4 days straight.
  • Need to show a photo ID to buy it in the drugstore and there is a limit on how much you can buy each visit.
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
Tips from our pharmacists for people taking the medication
SudafedNasonex
  • Starts working in 30 minutes.
  • You need to show an ID to buy Sudafed (Pseudoephedrine) in the drugstore because it contains pseudoephedrine.
  • Follow age-specific dosing instructions on how much to take. Don't take more than recommended on the package.
  • Don't take Sudafed (Pseudoephedrine) too close to bedtime since it can keep you awake.
  • Can cause an irregular or fast heartbeat, and can raise your blood pressure.
  • Talk to your doctor if your symptoms don't get better in 1 week.
  • Use Nasonex (Mometasone) once a day, following age-specific recommendations on how many sprays to use. Don't take more than prescribed.
  • Blow your nose before using.
  • Can cause thrush (a fungal infection) inside your nose and throat. Can also cause nosebleeds, a sore throat, and headaches.
  • Needs to be used regularly during allergy season for it to work. It can take 1 to 2 weeks for the medicine to start working fully.
  • Check with your doctor or pharmacist on how to use the nasal spray the right way.
  • Shake well before using it. Before the first use, prime the bottle by spraying it until you see a fine mist.
Learn more
More about SudafedSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Sudafed (pseudoephedrine)?
Worth itNot sureNot worth it
More about NasonexSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Nasonex (mometasone)?
Worth itNot sureNot worth it