Compare Sulfasalazine vs. Remicade

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Azulfidine
(sulfasalazine)

Remicade
(infliximab)

Reduces inflammation. Azulfidine (Sulfasalazine) is used for moderate to severe inflammatory bowel conditions, and with other meds for treating rheumatoid arthritis.Calms down your immune system. Remicade (infliximab) is an effective treatment for many autoimmune diseases, but you can have serious side effects.
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Coupons for Sulfasalazine
Best available price for 120 (500mg) tablets of sulfasalazine
Coupons for Remicade
Best available price for 18 (100mg) vials of remicade
Reviews & ratings
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Have you used Azulfidine (sulfasalazine)?
Worth itNot sureNot worth it
Reviews for Remicade
76%
-76% worse vs. Sulfasalazine
62%
-62% worse vs. Sulfasalazine
15%
+15% better vs. Sulfasalazine
Have you used Remicade (infliximab)?
Worth itNot sureNot worth it
Side effects
SulfasalazineRemicade

We haven’t found good data for Sulfasalazine side effects.

FDA side effect reports for Sulfasalazine »
  • Upper airway infection 7%
  • Nausea 1%
  • Headache 4%
  • Sinus infection 6%
  • Sore throat 4%
  • Coughinng 4%
  • Abdominal pain 4%
  • Bronchitis 1%
  • Rash 5%
More Remicade side effects »
How it works
SulfasalazineRemicade
Azulfidine (Sulfasalazine) is an anti-inflammatory drug that reduces inflammation and pain. It treats inflammatory bowel diseases and rheumatoid arthritis.Remicade (infliximab) blocks a protein in your immune system called TNF (tumor necrosis factor) that causes inflammation.
Type of medication
SulfasalazineRemicade
Prescription onlyPrescription only
Available as
SulfasalazineRemicade
  • Pill
  • Extended release
  • Injection
Used for
SulfasalazineRemicade
Risk factors for serious side effects
SulfasalazineRemicade
    Detailed Azulfidine (sulfasalazine) risks & warnings »
    • Taking other immunosuppressant drugs
    • Age 65 or older
    • Comorbidities
    • History of malignancy
    Detailed Remicade (infliximab) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Food
    SulfasalazineRemicade
    • Swallow tablets whole, and take after a meal with a full glass of water.
    No food related info.
    Kidneys and liver
    SulfasalazineRemicade
    • Severe hypersensitivity reactions can include internal organ involvement, such as hepatitis (liver), nephritis (kidney), myocarditis (heart), blood abnormalities, or pneumonitis (lungs).
    • Azulfidine (Sulfasalazine) isn't a good option if you have kidney or liver disease.
    No kidneys and liver related info.
    Weight
    SulfasalazineRemicade
    No weight related info.
    • Although rare, Remicade (infliximab) can hurt your liver. If you have appetite/weight loss, stomach discomfort, vomiting, or dark urine, talk to your doctor. If you have yellowing of skin/eyes, talk to your doctor right away.
    Upsides and benefits
    SulfasalazineRemicade
    • When taken consistently, Azulfidine (Sulfasalazine) can control your symptoms of ulcerative colitis and other bowel diseases.
    • Azulfidine (Sulfasalazine) is usually used in combination with other medications to control rheumatoid arthritis.
    • People taking Remicade (infliximab) for ulcerative colitis, Crohn's disease, rheumatoid arthritis and other autoimmune conditions had more clinical response, clinical remission and symptom improvement compared to people who did not take Remicade (infliximab).
    • People who were also taking steroids for treatment were able to discontinue steroid use while taking Remicade (infliximab).
    • Remicade (infliximab) has almost two decades of clinical trial data and real-life experience with many people who have used it.
    • After the initial dosing, you only need to take Remicade (infliximab) every 6-8 weeks, depending on your condition.
    • Compared to other medications used to treat autoimmune conditions, Remicade (infliximab) has not been associated with as many harmful effects during pregnancy and breastfeeding.
    Downsides and risks
    SulfasalazineRemicade
    • You need to have blood tests every 3 months when taking Azulfidine (Sulfasalazine).
    • Azulfidine (Sulfasalazine) isn't a good option if you have kidney or liver disease.
    • Can't take Azulfidine (Sulfasalazine) if you are allergic to aspirin or sulfa medications.
    • Azulfidine (Sulfasalazine) shouldn't be used if you are breastfeeding.
    • You have to receive this medication at your doctor's office or clinic. You might need to be tested regularly for tuberculosis.
    • Remicade (infliximab) lowers your ability to fight infection and can cause serious illness. The risk is greater if you take other drugs that lower your immune system, or have a history of diabetes or tuberculosis.
    • Remicade (infliximab) can in some cases worsen symptoms of heart failure or neurologic conditions. People 65 years and older may have more side effects from this medication.
    • In rare cases, Remicade (infliximab) has been associated with cancers in children and adolescents.
    • No generic available, so it can be costly.
    Tips from our pharmacists for people taking the medication
    SulfasalazineRemicade
    • Don't use if you are allergic to sulfa drugs or aspirin.
    • Swallow tablets whole, and take after a meal with a full glass of water.
    • Drink at least six glasses of water daily while on this.
    • Continue to take Azulfidine (Sulfasalazine) even once you feel better.
    • Read the information that come with your medication in the drugstore since there are many conditions you should be aware of before taking Azulfidine (Sulfasalazine).
    • Can cause an orange color in your urine or skin.
    • Remicade (infliximab) can in some cases cause a serious allergic reaction either immediately or several days after the treatment. Your doctor can give you medicines that will lower this risk.
    • Your doctor will test you for tuberculosis before taking Remicade (infliximab) and regularly during treatment.
    • Remicade (infliximab) lowers your immune system's ability to fight infections, so it's important to let your doctor know if you notice a fever, cough, or flu-like symptoms.
    • You should not receive any live vaccines while taking Remicade (infliximab). Tell your doctor that you are taking Remicade (infliximab) before receiving any vaccines.
    • If you have any signs or new or worsening symptoms such as heart, neurological, or autoimmune conditions, talk to your doctor. Tell your doctor about symptoms such as bruising or bleeding.
    Learn more
    More about SulfasalazineSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Azulfidine (sulfasalazine)?
    Worth itNot sureNot worth it
    More about RemicadeSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Remicade (infliximab)?
    Worth itNot sureNot worth it