Compare Sustiva vs. Viramune

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Sustiva (efavirenz)

Works with other medicines to treat HIV infection.

Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.

No information currently available
  • If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
  • Only taken once daily.
  • Sustiva (efavirenz) is available in combination tablets.
  • Can be used in patients with mild to moderate kidney damage.
  • Can be used in children who are at least 3 months old.
No information currently available
  • Not suggested for women who plan on becoming pregnant.
  • Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
  • Cannot be taken alone for treatment of HIV.
No information currently available
Used for
  • HIV infection
Dosage forms
  • Pill
  • Pill
  • Liquid
  • Extended release
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Side effects
8possible side effects
  • Skin rash
  • Diarrhea
  • Pain
  • Nausea
  • Dizziness
  • Itching
  • Fatigue
  • Headache
See more detailed side effects
The Viramune (Nevirapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Central nervous system (CNS) effects

    Starting Sustiva (efavirenz) for the first few weeks.

    ...and 1 more risk factors

  • Fat redistribution

    HIV treatment

  • Liver damage

    History of liver damage

    ...and 1 more risk factors

  • Immune reconstitution syndrome


    ...and 3 more risk factors

  • Psychiatric effects

    History of mental illness

    ...and 1 more risk factors

  • Rash

    History of severe skin reactions

    ...and 1 more risk factors

See more detailed risks and warnings
No information currently available