Compare Sustiva vs. Viramune

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Works with other medicines to treat HIV infection. Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.Coming soon.
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Coupons for Sustiva
Best available price for 90 (200mg) capsules of sustiva
Coupons for Viramune
Best available price for 60 (200mg) tablets of nevirapine
Reviews & ratings
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Have you used Sustiva (efavirenz)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Viramune (nevirapine)?
Worth itNot sureNot worth it
Side effects
  • Skin rash 16%
  • Diarrhea 14%
  • Pain 13%
  • Nausea 10%
  • Dizziness 9%
  • Itching 9%
  • Fatigue 8%
  • Headache 8%
More Sustiva side effects »

We haven’t found good data for Viramune side effects.

FDA side effect reports for Viramune »
How it works
Sustiva (efavirenz) is a Non-Nucleoside reverse transcriptase inhibitor (NNRTI). It treats HIV by stopping the virus from replicating within cells in your immune system.Coming soon.
Type of medication
Available as
  • Pill
  • Pill
  • Liquid
  • Extended release
Used for
  • HIV Infection
Risk factors for serious side effects
  • Starting Sustiva (efavirenz) for the first few weeks.
  • Taking alcohol or other drugs that also affect your nervous system
  • HIV treatment
  • History of liver damage
  • Alcohol intake
Detailed Sustiva (efavirenz) risks & warnings »
    Coming soon.

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Kidneys and liver
    • Liver damage has been reported in patients who use Sustiva (efavirenz). Your doctor might do blood tests to check your liver regularly. If you notice yellowing of the eyes or the skin, or dark urine, talk to your doctor right away.
    • Can be used in patients with mild to moderate kidney damage.
    No kidneys and liver related info.
    • Some patients experience central nervous system side effects when starting Sustiva (efavirenz), such as dizziness, trouble sleeping, difficulty concentrating, drowsiness, and strange dreams. Taking Sustiva (efavirenz) at bedtime will help lower the risk of experiencing these side effects. These symptoms are common in the first few weeks of starting treatment and usually go away. If symptoms don't improve or are preventing you from taking your medications regularly, let your doctor know.
    No sleep related info.
    Upsides and benefits
    • If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
    • Only taken once daily.
    • Sustiva (efavirenz) is available in combination tablets.
    • Can be used in patients with mild to moderate kidney damage.
    • Can be used in children who are at least 3 months old.
    Coming soon
    Downsides and risks
    • Not suggested for women who plan on becoming pregnant.
    • Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
    • Cannot be taken alone for treatment of HIV.
    Coming soon
    Tips from our pharmacists for people taking the medication
    • Side effects such as dizziness, insomnia, and/or abnormal dreams are common within the first few weeks of starting Sustiva (efavirenz). Talk to your doctor if these side effects last longer or are preventing you from taking your medication regularly.
    • Should be taken on an empty stomach at bedtime to reduce side effects.
    • Women taking Sustiva (efavirenz) should be on effective form(s) of birth control, as Sustiva (efavirenz) can cause birth defects.
    • If swallowing the capsule is difficult, you may open the capsules and sprinkle/mix the contents over a small amount of food (eg. applesause, yogurt) before taking.
    • Talk to your doctor or pharmacist before starting any new medication while on Sustiva (efavirenz) to prevent drug interactions.
    • Keep your regularly scheduled doctor and lab appointments. These help ensure your medication is working well and safely.
    Coming soon
    Learn more
    More about SustivaSide effectsAlternativesFDA package insert
    Have you used Sustiva (efavirenz)?
    Worth itNot sureNot worth it
    More about ViramuneSide effectsFDA package insert
    Have you used Viramune (nevirapine)?
    Worth itNot sureNot worth it