Compare Tagamet vs. Rolaids

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tagamet
(cimetidine)

Rolaids
(calcium carbonate / magnesium hydroxide)

Relieves heartburn and acid tummy. Tagamet (Cimetidine) works well for heartburn but may not last as long or start working as quickly as other antacids.Relieves heartburn and acid tummy. Rolaids (Calcium Carbonate / Magnesium Hydroxide) gives quick relief for heartburn, but don't expect it to last all day.
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Reviews & ratings
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4.64Tagamet
Reviews for Tagamet (cimetidine)
63%
of people (All ages) say Tagamet (cimetidine) is worth it
36%
say it works well
12%
say it's a big hassle
632 reviews
Have you used Tagamet (cimetidine)?
Worth itNot sureNot worth it
Reviews for Rolaids (calcium carbonate / magnesium hydroxide)
75%
+12% better vs. Tagamet (cimetidine)
37%
+1% better vs. Tagamet (cimetidine)
7%
+5% better vs. Tagamet (cimetidine)
1089 reviews
Have you used Rolaids (calcium carbonate / magnesium hydroxide)?
Worth itNot sureNot worth it
Side effects
TagametRolaids
  • Abnormally large breasts in males 4%
  • Headache 2%
More Tagamet side effects »

We haven’t found good data for Rolaids side effects.

FDA side effect reports for Rolaids »
How it works
TagametRolaids
Tagamet (Cimetidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.Rolaids (Calcium Carbonate / Magnesium Hydroxide) is an antacid. It counteracts the effects of stomach acid to relieve heartburn and acid tummy (indigestion).
Type of medication
TagametRolaids
Prescription or OTC
Over-the-counter
Available as
TagametRolaids
  • Pill
  • Liquid
  • Chewable tablet
  • Liquid
Used for
TagametRolaids
Risk factors for serious side effects
TagametRolaids
    • Current kidney disease
    • Current liver disease
    • Age 50 or older
    • Current severe illness
      • Autoimmune disease
      • HIV or AIDS
      • Organ transplant
      • People without a spleen
      Detailed Tagamet (cimetidine) risks & warnings »
        • Current kidney disease
        • Kidney dialysis
        • Hyperparathyroid disease
        • Taking high doses of Vitamin D
        • Previous kidney stones
        Detailed Rolaids (calcium carbonate / magnesium hydroxide) risks & warnings »
        Pregnancy

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        Interactions
        TagametRolaids
        • Has more drug interactions than zantac and pepcid.
        No interactions related info.
        Kidneys and liver
        TagametRolaids
        • People with kidney disease may need to take a lower dose.
        • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
        • If you have kidney or hyperparathyroid disease Rolaids (Calcium Carbonate / Magnesium Hydroxide) can build up in your blood. This may can cause toxic levels of calcium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Rolaids (Calcium Carbonate / Magnesium Hydroxide); a different antacid would be better for you.
        • Rolaids (Calcium Carbonate / Magnesium Hydroxide) contains calcium. Calcium can be an ingredient in some kidney stones. If you have had kidney stones in the past (especially the calcium-containing kind) be careful using Rolaids (Calcium Carbonate / Magnesium Hydroxide). Use the lowest dose for the shortest time possible or just play it safe and use a different antacid instead.
        Upsides and benefits
        TagametRolaids
        • Most people can take Cimetidine without any noticeable day-to-day side effects.
        • Cimetidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
        • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
        • Available as both a generic and over-the-counter option, so it's pretty affordable.
        • Works really fast.
        • Available over the counter without a prescription.
        • Cheap.
        Downsides and risks
        TagametRolaids
        • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Cimetidine.
        • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Cimetidine (H2 blockers).
        • Has more drug interactions than zantac and pepcid.
        • Although rare, Cimetidine can cause large breasts or impotence for men who need to use high doses for 6 months or more. It's reversible though and should go away when you stop or if you change medication.
        • Doesn't last very long.
        • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
        • Some chalky aftertaste.
        Tips from our pharmacists for people taking the medication
        TagametRolaids
        • Works best if you take it with a full glass of water.
        • Starts working in one hour.
        • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
        • People with kidney disease may need to take a lower dose.
        • Tell your doctor all of the medications that you use before taking Cimetidine to avoid drug interactions.
        • Take at the first sign of discomfort.
        • You might need to take more than once a day but pay attention to the instructions on your bottle to avoid overdosing.
        • Take 1-2 hours apart from other medication that you take by mouth.
        • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
        • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
        • Don't take if you have high blood calcium levels.
        Learn more
        More about TagametSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Tagamet (cimetidine)?
        Worth itNot sureNot worth it
        More about RolaidsSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Rolaids (calcium carbonate / magnesium hydroxide)?
        Worth itNot sureNot worth it