Compare Tegretol vs. Imitrex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol
(carbamazepine)

Imitrex
(sumatriptan)

Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Treats migraine headaches. Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.
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Prices and coupon for 60 (200mg) tablets of carbamazepine
Coupons for
Prices and coupon for 1 (9 tablets of 100mg) dose pack of sumatriptan
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48Tegretol
Reviews for Tegretol (carbamazepine)
56%
of people (All ages) say Tegretol (carbamazepine) is worth it
43%
say it works well
23%
say it's a big hassle
Have you used Tegretol (carbamazepine)?
Worth itNot sureNot worth it
Reviews for Imitrex (sumatriptan)
74%
+18% better vs. Tegretol (carbamazepine)
68%
+25% better vs. Tegretol (carbamazepine)
19%
+4% better vs. Tegretol (carbamazepine)
Have you used Imitrex (sumatriptan)?
Worth itNot sureNot worth it
Side effects
TegretolImitrex
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 18%
  • Vomiting 15%
  • Lack of muscle coordination 15%
  • Constipation 5%
  • Itching 6%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Rash 3%
More Tegretol side effects »
  • Pain and other pressure sensations 2%
  • Atypical sensations 1%
  • Paresthesia (all types) 1%
  • Sensation warm/cold 1%
  • Pain - location specified 1%
  • Malaise/fatigue 2%
  • Chest - pain/tightness/pressure and/or heaviness 1%
  • Neck/throat/jaw - pain/ tightness/pressure 2%
  • Other - pressure/tightness/ heaviness 1%
  • Vertigo 2%
More Imitrex side effects »
How it works
TegretolImitrex
Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Imitrex (Sumatriptan) is a triptan medication that treats migraine headaches. It releases serotonin, which lowers the inflammation that causes headaches.
Type of medication
TegretolImitrex
Prescription only
Prescription only
Available as
TegretolImitrex
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Injection
  • Nasal spray
Used for
TegretolImitrex
Risk factors for serious side effects
TegretolImitrex
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (carbamazepine) risks & warnings »
      • History of heart problems
      • High blood pressure
      • High cholesterol
      • Diabetes
      • Being overweight or obese
      • Smoking
      • History of heart problems
      • High blood pressure
      • High cholesterol
      • Diabetes
      • Being overweight or obese
      • Smoking
        • Patients taking SSRIs and SNRIs
        • History of high blood pressure
        • History of seizures
        Detailed Imitrex (sumatriptan) risks & warnings »
        Pregnancy

        Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Interactions
        TegretolImitrex
        • Interacts with many other medicines and supplements.
        No interactions related info.
        Sleep
        TegretolImitrex
        No sleep related info.
        • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
        Upsides and benefits
        TegretolImitrex
        • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
        • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
        • May be helpful in stabilizing mood for people with bipolar disorder.
        • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
        • A combination of forms can be used if symptoms do not improve.
        • The nasal spray and injectable forms work very quickly.
        • It's generally safe to use if you are pregnant.
        • Comes in a generic form, so it can be pretty cheap.
        Downsides and risks
        TegretolImitrex
        • Interacts with many other medicines and supplements.
        • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
        • Can cause blurry vision, dizziness, and upset stomach.
        • Not safe to use if you're pregnant.
        • Requires routine blood tests to see how the medicine is affecting your body.
        • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
        • Does not prevent migraine headaches; it only treats them once they start.
        • Must wait 1 hour before using second injection.
        • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
        • Need to have your blood pressure checked often, especially if you're pregnant.
        Tips from our pharmacists for people taking the medication
        TegretolImitrex
        • For the first week, avoid activities that require you to be alert.
        • Report skin rashes or blistering immediately.
        • Don't use if pregnant.
        • Requires routine blood tests.
        • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
        • Takes up to 5 weeks to feel full effects on mood.
        • Take it as soon as your headache starts.
        • If you use the nasal spray, be sure to blow your nose before using it.
        • If you use the patch, put it on a dry area free of scars, tattoos, or other cuts and scrapes. Be sure to press the button to activate it.
        • If you use the injection, you can use a second injection if you still have a headache after an hour. If you have symptoms 2 hours after the injection, switch to the pill version.
        • Imitrex (Sumatriptan) can make you drowsy, so avoid activities that need you to be fully alert until you know how it affects you.
        • Lie down in a dark room after taking Imitrex (Sumatriptan) to help ease the pain.
        Learn more
        More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Tegretol (carbamazepine)?
        Worth itNot sureNot worth it
        More about ImitrexSide effectsReviews & ratingsFDA package insert
        Have you used Imitrex (sumatriptan)?
        Worth itNot sureNot worth it