Compare Tegretol vs. Keppra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol (Carbamazepine)

Prescription only

Keppra (Levetiracetam)

Prescription only
Prevents seizures, stabilizes mood, and relieves nerve pain.

Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.

4.5/ 7 average rating with 61 reviewsforTegretol
Prevents seizures.

Keppra (Levetiracetam) is effective for preventing seizures in people with epilepsy. Compared to other anti-seizure medications, it has few drug interactions and you don’t need to get your levels checked.

6.2/ 7 average rating with 21 reviewsforKeppra
Upsides
  • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
  • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
  • May be helpful in stabilizing mood for people with bipolar disorder.
  • Lowers the frequency of seizures, including partial-onset, generalized tonic-clonic, and myoclonic seizures.
  • Unlike many other medications for epilepsy, this has very few drug interactions, so your other medicines shouldn't be affected.
  • If you have trouble swallowing tablets, Keppra (Levetiracetam) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
Downsides
  • Interacts with many other medicines and supplements.
  • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
  • Can cause blurry vision, dizziness, and upset stomach.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
  • It’s important to take your dose on time so that Keppra (Levetiracetam) has consistent levels in your body.
  • May not be the best drug to take if you have a history of psychiatric issues, such as depression or bipolar disorder.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Keppra (Levetiracetam) is only FDA-approved to be taken with other medicines to treat epilepsy.
Used for
Dosage forms
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release
  • Liquid
Price
Lowest price near you
$32
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Lowest price near you
$14.75
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Reviews
61 
56%
think this treatment is worth it
43%
think this treatment works well
23%
think this treatment is a hassle

Have you used Tegretol (Carbamazepine)?

Leave a review
21 
33%
think this treatment is worth it
81%
think this treatment works well
33%
think this treatment is a hassle

Have you used Keppra (Levetiracetam)?

Leave a review
Side effects
10possible side effects
  • Dizziness
    44%
  • Somnolence
    32%
  • Nausea
    28%
  • Vomiting
    18%
  • Ataxia
    15%
  • Constipation
    10%
  • Pruritus
    8%
  • Dry Mouth
    8%
  • Asthenia
    8%
  • Rash
    7%
See more detailed side effects
9possible side effects
  • Somnolence
    12%
  • Neck pain
    8%
  • Any side effect
    8%
  • Pharyngitis
    7%
  • Vertigo
    5%
  • Influenza
    5%
  • Depression
    5%
  • Anxiety
    3%
  • Depressed mood
    2%
See more detailed side effects
Risks and warnings
  • Serious skin rash

    People also taking Depakote

    ...and 1 more risk factors

  • Suicidal thoughts or behavior

    History of depression

  • Serious allergic reactions

    European, Chinese, or Japanese ancestry

  • Mental changes due to low sodium

    Age 65 years or older

  • Withdrawal seizures

    Stopping Tegretol (Carbamazepine) suddenly

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    History of depression

  • Driving impairment

    Starting the first month of therapy

    ...and 2 more risk factors

  • Withdrawal seizures

    Stopping Keppra (Levetiracetam) suddenly

  • Psychiatric side effects

    History of psychiatric problems

    ...and 1 more risk factors

See more detailed risks and warnings