Compare Tegretol vs. Lamictal

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol
(Carbamazepine)

Lamictal
(Lamotrigine)

Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Prevents seizures and stabilizes mood. Lamictal (Lamotrigine) is most useful for treating severe seizure disorders, and for bipolar disorder with more depression symptoms than manic symptoms. Just be careful to increase your dose slowly to avoid skin rash.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48Tegretol
Reviews for Tegretol (Carbamazepine)
56%
of people (All ages) say Tegretol (Carbamazepine) is worth it
43%
say it works well
23%
say it's a big hassle
Have you used Tegretol (Carbamazepine)?
Worth itNot sureNot worth it
Reviews for Lamictal (Lamotrigine)
66%
+10% better vs. Tegretol (Carbamazepine)
58%
+15% better vs. Tegretol (Carbamazepine)
18%
+5% better vs. Tegretol (Carbamazepine)
184 reviews
Have you used Lamictal (Lamotrigine)?
Worth itNot sureNot worth it
Side effects
TegretolLamictal
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 18%
  • Vomiting 15%
  • Lack of muscle coordination 15%
  • Constipation 5%
  • Itching 6%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Rash 3%
More Tegretol side effects »
  • Dizziness 25%
  • Headache 9%
  • Double vision 21%
  • Lack of muscle coordination 16%
  • Nausea 9%
  • Blurred vision 11%
  • Inflammation inside the nose 5%
  • Drowsiness 7%
  • Sore throat 1%
  • Rash 5%
More Lamictal side effects »
How it works
TegretolLamictal
Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Lamictal (Lamotrigine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to calm nerve activity in the brain.
Type of medication
TegretolLamictal
Prescription only
Prescription only
Available as
TegretolLamictal
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release
  • Chewable tablet
  • Dissolving tablet
Used for
TegretolLamictal
Risk factors for serious side effects
TegretolLamictal
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (Carbamazepine) risks & warnings »
      • History of depression
      • People also taking Depakote
      • Taking more than the prescribed dose
      • Increasing the dose too quickly
            • Taking birth control pills
            • Stopping Lamictal (Lamotrigine) suddenly
            Detailed Lamictal (Lamotrigine) risks & warnings »
            Pregnancy

            Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

            Interactions
            TegretolLamictal
            • Interacts with many other medicines and supplements.
            No interactions related info.
            Food
            TegretolLamictal
            No food related info.
            • Take with food to avoid upset stomach.
            Upsides and benefits
            TegretolLamictal
            • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
            • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
            • May be helpful in stabilizing mood for people with bipolar disorder.
            • Effective at lowering the frequency of seizures in people with epilepsy or Lennox-Gestaut syndrome. Typically used together with other medications for severe seizure disorders.
            • Works best for partial, tonic-clonic, and absence seizures.
            • A first-line treatment for bipolar disorder. Effective long-term treatment for stabilizing mood. Prevents both depressive and manic episodes, but the effect is greater for preventing depression.
            • Doesn't require routine blood tests.
            Downsides and risks
            TegretolLamictal
            • Interacts with many other medicines and supplements.
            • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
            • Can cause blurry vision, dizziness, and upset stomach.
            • Not safe to use if you're pregnant.
            • Requires routine blood tests to see how the medicine is affecting your body.
            • Can cause double vision, dizziness, sleepiness, and headache.
            • Has the risk of a rare but life-threatening rash.
            • Can make hormonal birth control less effective.
            • Might be less effective than other medicines for treating manic episodes (acute mania) in people with bipolar disorder.
            Tips from our pharmacists for people taking the medication
            TegretolLamictal
            • For the first week, avoid activities that require you to be alert.
            • Report skin rashes or blistering immediately.
            • Don't use if pregnant.
            • Requires routine blood tests.
            • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
            • Takes up to 5 weeks to feel full effects on mood.
            • Follow dose adjustments set by your doctor to minimize skin rash.
            • Take with food to avoid upset stomach.
            • Report rash, blurry vision, fever, persistent headache, or neck stiffness to your doctor.
            • Makes hormonal birth control less effective.
            • Takes 4 to 6 weeks to feel full effects on mood.
            Learn more
            More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
            Have you used Tegretol (Carbamazepine)?
            Worth itNot sureNot worth it
            More about LamictalSide effectsReviews & ratingsAlternativesFDA package insert
            Have you used Lamictal (Lamotrigine)?
            Worth itNot sureNot worth it