Compare Tegretol vs. Neurontin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol
(Carbamazepine)

Neurontin
(Gabapentin)

Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Treats tingling and burning nerve pain. Neurontin (Gabapentin) is an old seizure disorder medicine that's now used to treat nerve-related pain caused by different conditions.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.5576923076923075Tegretol
Reviews for Tegretol (Carbamazepine)
58%
of people say Tegretol (Carbamazepine) is worth it
42%
say it works well
21%
say it's a big hassle
Reviews for Neurontin (Gabapentin)
57%
1% vs. Tegretol (Carbamazepine)
39%
3% vs. Tegretol (Carbamazepine)
19%
+2% vs. Tegretol (Carbamazepine)
Side effects
TegretolNeurontin
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 19%
  • Vomiting 15%
  • Itching 6%
  • Constipation 5%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Blurred vision 4%
  • Rash 3%
More Tegretol side effects »
  • Dizziness 21%
  • Drowsiness 16%
  • Lack of muscle coordination 7%
  • Leg or ankle swelling 6%
  • Fatigue 6%
  • Hostility 5%
  • Involuntary eye movement 4%
  • Double vision 4%
  • Tremor 4%
  • Dry mouth 4%
More Neurontin side effects »
How it works
TegretolNeurontin
Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Neurontin (Gabapentin) is an antiepileptic and nerve pain reliever. Researchers don't know exactly how it works, but it has a similar structure to GABA, a neurotransmitter that calms nerves in the brain and spinal cord.
Type of medication
TegretolNeurontin
AnticonvulsantPrescription only
Anticonvulsant
GABA analog
Prescription only
Available as
TegretolNeurontin
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Oral solution
Used for (click to learn more)
TegretolNeurontin
Risk factors for serious side effects
TegretolNeurontin
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (Carbamazepine) risks & warnings »
        • Children ages 3 to 12
          • Taking with alcohol or drugs
          • Stopping Neurontin (Gabapentin) suddenly
          Detailed Neurontin (Gabapentin) risks & warnings »
          Pregnancy category
          TegretolNeurontin
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.
          • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
          Food
          No specific food-related info.
          • Take the extended-release tablet with food.
          Kidneys and liver
          No specific kidneys and liver-related info.No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.
          • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
          Weight
          No specific weight-related info.No specific weight-related info.
          Upsides and benefits
          TegretolNeurontin
          • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
          • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
          • May be helpful in stabilizing mood for people with bipolar disorder.
          • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
          • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
          • It's available as a generic, so it's less expensive than similar medications.
          Downsides and risks
          TegretolNeurontin
          • Interacts with many other medicines and supplements.
          • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
          • Can cause blurry vision, dizziness, and upset stomach.
          • Not safe to use if you're pregnant.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Neurontin (Gabapentin) is likely to cause some side effects, including memory problems, drowsiness, dizziness, or confusion.
          • You can't skip or miss doses since suddenly stopping Neurontin (Gabapentin) can cause seizures. This is even more likely if you drink alcohol, so it might not be the best medication for heavy drinkers.
          Tips from our pharmacists for people taking the medication
          TegretolNeurontin
          • For the first week, avoid activities that require you to be alert.
          • Report skin rashes or blistering immediately.
          • Don't use if pregnant.
          • Requires routine blood tests.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Takes up to 5 weeks to feel full effects on mood.
          • Side effects are common, but usually manageable.
          • Don't drive while taking Neurontin (Gabapentin) until you know how the medication affects you.
          • Neurontin and generic forms of Gabapentin have the same ingredients as Gralise and Horizant, but are dosed differently. Make sure you know which form you're taking since they are used for different purposes.
          • Take the extended-release tablet with food.
          • Stop taking Neurontin (Gabapentin) slowly over at least one week to avoid getting withdrawal symptoms.
          Learn more
          More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
          More about NeurontinSide effectsReviews & ratingsAlternativesFDA package insert