Compare Tegretol vs. Topamax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol
(Carbamazepine)

Qudexy Xr
(Topiramate)

Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Prevents seizures and migraine headaches. Qudexy Xr (Topiramate) is useful for preventing seizures and migraines, and doesn't require blood tests while you're on it.
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Reviews & ratings
Button Group. All currently active
Button Group. All currently active
4.5576923076923075Tegretol
Reviews for Tegretol (Carbamazepine)
58%
of people say Tegretol (Carbamazepine) is worth it
42%
say it works well
21%
say it's a big hassle
Reviews for Qudexy Xr (Topiramate)
54%
4% vs. Tegretol (Carbamazepine)
52%
+10% vs. Tegretol (Carbamazepine)
33%
12% vs. Tegretol (Carbamazepine)
Side effects
TegretolTopamax
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 19%
  • Vomiting 15%
  • Itching 6%
  • Constipation 5%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Blurred vision 4%
  • Rash 3%
More Tegretol side effects »
  • Tingling sensation 45%
  • Slowed-down thinking and movements 19%
  • Dizziness 17%
  • Drowsiness 17%
  • Fatigue 17%
  • Change in taste 14%
  • Difficulty with concentration/attention 13%
  • Nervousness 12%
  • Difficulty with memory 11%
  • Vision abnormal 11%
More Topamax side effects »
How it works
TegretolTopamax
Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Qudexy Xr (Topiramate) is an antiepileptic. Researchers don't know exactly how it works, but it seems to affect multiple parts of the brain to control seizures and migraines.
Type of medication
TegretolTopamax
AnticonvulsantPrescription only
AnticonvulsantPrescription only
Available as
TegretolTopamax
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release capsule
Used for (click to learn more)
TegretolTopamax
Risk factors for serious side effects
TegretolTopamax
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (Carbamazepine) risks & warnings »
      • History of depression
        • Children
        • History of metabolic disorders
        • People also taking Depakote
        • Low-carb diet
        • Dehydration
        • Drug interactions
          • Stopping Qudexy Xr (Topiramate) suddenly
          Detailed Qudexy Xr (Topiramate) risks & warnings »
          Pregnancy category
          TegretolTopamax
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          No specific food-related info.No specific food-related info.
          Kidneys and liver
          No specific kidneys and liver-related info.
          • A few people will get kidney stones.
          • Qudexy Xr (Topiramate) may increase your risk for kidney stones. Stay well-hydrated to lower your risk.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          No specific sleep-related info.No specific sleep-related info.
          Weight
          No specific weight-related info.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          Upsides and benefits
          TegretolTopamax
          • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
          • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
          • May be helpful in stabilizing mood for people with bipolar disorder.
          • Used on its own or with other antiepileptic medicines to lower the frequency of seizures, especially for people with tonic-clonic or partial seizures, or Lennox-Gestaut syndrome.
          • Helpful in preventing frequent migraine headaches.
          • Doesn't need routine blood tests.
          Downsides and risks
          TegretolTopamax
          • Interacts with many other medicines and supplements.
          • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
          • Can cause blurry vision, dizziness, and upset stomach.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Not safe to use if you're pregnant.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          • A few people will get kidney stones.
          • Not safe to use if you're pregnant.
          Tips from our pharmacists for people taking the medication
          TegretolTopamax
          • Report skin rashes or blistering immediately.
          • Requires routine blood tests.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Takes up to 5 weeks to feel full effects on mood.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          • Can cause tingling skin sensations and reduced appetite.
          • Report any confusion, decreased sweating, fever, or changes in behavior or vision.
          • Takes 3 to 4 weeks to feel full effects on mood.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          Learn more
          More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
          More about TopamaxSide effectsReviews & ratingsAlternativesFDA package insert