Compare Tegretol vs. Topamax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol
(Carbamazepine)

Qudexy Xr
(Topiramate)

Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.Prevents seizures and migraine headaches. Qudexy Xr (Topiramate) is useful for preventing seizures and migraines, and doesn't require blood tests while you're on it.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
4.48Tegretol
Reviews for Tegretol (Carbamazepine)
56%
of people (All ages) say Tegretol (Carbamazepine) is worth it
43%
say it works well
23%
say it's a big hassle
Have you used Tegretol (Carbamazepine)?
Worth itNot sureNot worth it
Reviews for Qudexy Xr (Topiramate)
52%
-4% worse vs. Tegretol (Carbamazepine)
50%
+7% better vs. Tegretol (Carbamazepine)
36%
-13% worse vs. Tegretol (Carbamazepine)
Have you used Qudexy Xr (Topiramate)?
Worth itNot sureNot worth it
Side effects
TegretolTopamax
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 18%
  • Vomiting 15%
  • Lack of muscle coordination 15%
  • Constipation 5%
  • Itching 6%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Rash 3%
More Tegretol side effects »
  • Ear, nose, or throat infection 16%
  • Diarrhea 8%
  • Weight decrease 7%
  • Difficulty with concentration/attention 7%
  • Inflammation inside the nose 5%
  • Tingling sensation 3%
  • Infection 3%
  • Infection viral 3%
  • Rash 3%
  • Fatigue 17%
More Topamax side effects »
How it works
TegretolTopamax
Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.Qudexy Xr (Topiramate) is an antiepileptic. Researchers don't know exactly how it works, but it seems to affect multiple parts of the brain to control seizures and migraines.
Type of medication
TegretolTopamax
Prescription only
Prescription only
Available as
TegretolTopamax
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
  • Extended release capsule
Used for
TegretolTopamax
Risk factors for serious side effects
TegretolTopamax
  • People also taking Depakote
  • Asian ancestry
    • History of depression
    • European, Chinese, or Japanese ancestry
      • Age 65 years or older
      • Stopping Tegretol (Carbamazepine) suddenly
      Detailed Tegretol (Carbamazepine) risks & warnings »
      • History of depression
        • Children
        • History of metabolic disorders
        • People also taking Depakote
        • Low-carb diet
        • Dehydration
        • Drug interactions
          • Stopping Qudexy Xr (Topiramate) suddenly
          Detailed Qudexy Xr (Topiramate) risks & warnings »
          Pregnancy

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          Interactions
          TegretolTopamax
          • Interacts with many other medicines and supplements.
          No interactions related info.
          Kidneys and liver
          TegretolTopamax
          No kidneys and liver related info.
          • A few people will get kidney stones.
          • Qudexy Xr (Topiramate) may increase your risk for kidney stones. Stay well-hydrated to lower your risk.
          Weight
          TegretolTopamax
          No weight related info.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          Upsides and benefits
          TegretolTopamax
          • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
          • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
          • May be helpful in stabilizing mood for people with bipolar disorder.
          • Used on its own or with other antiepileptic medicines to lower the frequency of seizures, especially for people with tonic-clonic or partial seizures, or Lennox-Gestaut syndrome.
          • Helpful in preventing frequent migraine headaches.
          • Doesn't need routine blood tests.
          Downsides and risks
          TegretolTopamax
          • Interacts with many other medicines and supplements.
          • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
          • Can cause blurry vision, dizziness, and upset stomach.
          • Not safe to use if you're pregnant.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
          • A few people will get kidney stones.
          • Not safe to use if you're pregnant.
          Tips from our pharmacists for people taking the medication
          TegretolTopamax
          • For the first week, avoid activities that require you to be alert.
          • Report skin rashes or blistering immediately.
          • Don't use if pregnant.
          • Requires routine blood tests.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Takes up to 5 weeks to feel full effects on mood.
          • For the first week, avoid activities that require you to be alert.
          • Don't use if pregnant.
          • Can cause tingling skin sensations and reduced appetite.
          • Report any confusion, decreased sweating, fever, or changes in behavior or vision.
          • Takes 3 to 4 weeks to feel full effects on mood.
          Learn more
          More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Tegretol (Carbamazepine)?
          Worth itNot sureNot worth it
          More about TopamaxSide effectsReviews & ratingsAlternativesFDA package insert
          Have you used Qudexy Xr (Topiramate)?
          Worth itNot sureNot worth it