Compare Tegretol vs. Zonegran

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tegretol (Carbamazepine)

Prescription only

Zonegran (zonisamide)

Prescription only
Prevents seizures, stabilizes mood, and relieves nerve pain.

Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.

4.5/ 7 average rating with 61 reviewsforTegretol
Controls partial seizures.

Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can't be used by itself.

Upsides
  • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
  • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
  • May be helpful in stabilizing mood for people with bipolar disorder.
  • Available in generic.
  • Can be given once a day, so it's easier to remember.
  • You can take Zonegran (zonisamide) with or without food.
Downsides
  • Interacts with many other medicines and supplements.
  • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
  • Can cause blurry vision, dizziness, and upset stomach.
  • Not safe to use if you're pregnant.
  • Requires routine blood tests to see how the medicine is affecting your body.
  • Zonegran (zonisamide) has to be used with other medicines to help control your seizures. It's not used by itself.
  • Zonegran (zonisamide) is only approved in people age 16 or older.
  • Zonegran (zonisamide) can cause kidney stones; so you have to make sure you drink plenty of liquids.
  • Zonegran (zonisamide) can weaken your bones. Talk to your doctor about how to keep your bones strong.
  • Other medicines used to control seizures can interact with Zonegran (zonisamide), so your doctor might have to change the dosing of your medications.
Used for
Dosage forms
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
  • Pill
Price
Lowest price near you
$32
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Lowest price near you
$16.8
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Reviews
61 
56%
think this treatment is worth it
43%
think this treatment works well
23%
think this treatment is a hassle

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Side effects
10possible side effects
  • Dizziness
    44%
  • Somnolence
    32%
  • Nausea
    28%
  • Vomiting
    18%
  • Ataxia
    15%
  • Constipation
    10%
  • Pruritus
    8%
  • Dry Mouth
    8%
  • Asthenia
    8%
  • Rash
    7%
See more detailed side effects
10possible side effects
  • Sleepiness
    17%
  • Loss of appetite
    13%
  • Dizziness
    13%
  • Headache
    10%
  • Nausea
    9%
  • Agitation or Irritability
    9%
  • Fatigue
    8%
  • Tiredness
    7%
  • Stomach pain
    6%
  • Difficulty controlling movements
    6%
See more detailed side effects
Risks and warnings
  • Serious skin rash

    People also taking Depakote

    ...and 1 more risk factors

  • Suicidal thoughts or behavior

    History of depression

  • Serious allergic reactions

    European, Chinese, or Japanese ancestry

  • Mental changes due to low sodium

    Age 65 years or older

  • Withdrawal seizures

    Stopping Tegretol (Carbamazepine) suddenly

See more detailed risks and warnings
  • Sulfa medicine allergy

    Allergy to sulfonamides such as Septra or Bactrim

  • Heat stroke and less sweating

    Under age 18

  • Suicidal behavior

    Taking other medicines to control seizures

  • Higher blood acid

    Diarrhea

    ...and 2 more risk factors

See more detailed risks and warnings