Compare Tenex vs. Imitrex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tenex (Guanfacine)

Prescription only

Imitrex (Sumatriptan)

Prescription only
Treats ADHD and lowers blood pressure.

Tenex (Guanfacine) can be used to treat both blood pressure and ADHD, but it's not recommended as a first-line treatment for either problem.

Treats migraine headaches.

Imitrex (Sumatriptan) is an excellent choice for acute migraine relief, but you might need another medication to prevent headaches.

5.3/ 7 average rating with 31 reviewsforImitrex
Upsides
  • The same medication treats two different things, high blood pressure and attention deficit hyperactivity disorder (ADHD).
  • It's not a "controlled medication".
  • Used to control ADHD when stimulant medications haven't worked or can't be used due to other medical problems.
  • Available as a generic medication, so it should be more affordable than other options.
  • Comes in several forms. Ask your doctor if you should use the pill, nasal spray, patch, or injection.
  • A combination of forms can be used if symptoms do not improve.
  • The nasal spray and injectable forms work very quickly.
  • It's generally safe to use if you are pregnant.
  • Comes in a generic form, so it can be pretty cheap.
Downsides
  • Doesn't control ADHD as well as stimulants do, so it's used as a second-line medication.
  • Not a preferred drug to control blood pressure.
  • Can't be stopped suddenly, especially for blood pressure, since the blood pressure can dramatically increase.
  • The oral and nasal versions of Imitrex (Sumatriptan) have an unpleasant after-taste.
  • Does not prevent migraine headaches; it only treats them once they start.
  • Must wait 1 hour before using second injection.
  • Can cause rebound (more) headaches if Imitrex (Sumatriptan) is used too often.
  • Need to have your blood pressure checked often, especially if you're pregnant.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Injection
  • Nasal spray
Price
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$4
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$12.4
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Reviews
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31 
74%
think this treatment is worth it
68%
think this treatment works well
19%
think this treatment is a hassle

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Side effects
7possible side effects
  • Dry Mouth
    10%
  • Somnolence
    10%
  • Headache
    7%
  • Fatigue
    5%
  • Any side effect
    5%
  • Asthenia
    3%
  • Dizziness
    2%
See more detailed side effects
6possible side effects
  • Pain and other pressure sensations
    6%
  • Atypical sensations
    5%
  • Paresthesia (all types)
    3%
  • Sensation warm/cold
    3%
  • Pain - location specified
    2%
  • Malaise/fatigue
    2%
See more detailed side effects
Risks and warnings
  • Sedation

    Taking other medications that cause sedation or sleepiness

  • Rebound high blood pressure

    Stopping Tenex (Guanfacine) suddenly to treat high blood pressure

See more detailed risks and warnings
  • Tightening of blood vessels (myocardial angina, ischemia, or infarction)

    History of heart problems

    ...and 5 more risk factors

  • Stroke

    History of heart problems

    ...and 5 more risk factors

  • Serotonin syndrome

    Patients taking SSRIs and SNRIs

  • High blood pressure

    History of high blood pressure

  • Seizures

    History of seizures

See more detailed risks and warnings