Compare Testopel vs. Aveed

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Testopel
(testosterone implant)

Aveed
(testosterone undecanoate injection)

Treats low testosterone. The testosterone implant is a good option for long-term testosterone therapy, but it can be expensive, and it's really important that you get the right dose so your doctor doesn't have to remove pellets.Treats low testosterone. This testosterone injection is a first-choice treatment, but you have to get it in your doctor's office each time.
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Reviews & ratings
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Have you used Testopel (testosterone implant)?
Worth itNot sureNot worth it
Reviews for Aveed
41%
+39% better vs. Testopel
22%
+58% better vs. Testopel
18%
+18% better vs. Testopel
Have you used Aveed (testosterone undecanoate injection)?
Worth itNot sureNot worth it
Side effects
TestopelAveed

The Testopel FDA package insert doesn’t have numbers about how common side effects are.

More about Testopel side effects »
  • Acne 5%
  • Injection site pain 5%
  • Prostatic specific antigen increased 5%
  • Estradiol increased 3%
  • Hypogonadism 3%
  • Fatigue 2%
  • Irritability 2%
  • Hemoglobin increased 2%
  • Sleep difficulty 2%
  • Mood swings 2%
More Aveed side effects »
How it works
TestopelAveed
The testosterone implant works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.The testosterone injection works by adding or replacing the hormone testosterone in your body. Testosterone is responsible for causing and maintaining many of the changes in male bodies from puberty on.
Type of medication
TestopelAveed
Prescription onlyPrescription only
Available as
TestopelAveed
  • Implant pellet
  • Injection
Used for
TestopelAveed
  • Low Testosterone
  • Low Testosterone
Risk factors for serious side effects
TestopelAveed
    Coming soon.
    • Male
    • Enlarged prostate (benign prostatic hypertrophy)
    • Taking high doses of Aveed (Testosterone Undecanoate Injection)
    • Heart, liver or kidney disease
    Detailed Aveed (testosterone undecanoate injection) risks & warnings »
    Pregnancy

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

    Kidneys and liver
    TestopelAveed
    No kidneys and liver related info.
    • There have been reports of people on Aveed (Testosterone Undecanoate Injection) who have developed high levels of calcium in the blood, which can be bad for the kidneys. This can happen if you are unable to move around or if you have cancer. If you notice a metallic taste in your mouth, muscle or joint pain or a bad headache, talk to your doctor, since they may have to stop the medication.
    Pain
    TestopelAveed
    No pain related info.
    • If you're on Aveed (Testosterone Undecanoate Injection), and you notice pain in your abdomen, or if your skin or the whites of your eyes turn yellow, call your doctor immediately. This can be liver damage.
    Upsides and benefits
    TestopelAveed
    • Your doctor will give this shot to you every 3 months, so you don't have to worry about administering it yourself like some testosterone injections.
    • Unlike topical forms of testosterone, you don't have to worry about accidentally transferring this medication to another person's skin.
    • A first-choice treatment for low testosterone in men.
    • The first two shots are spaced out by a month, then each shot after that is given every 10 weeks.
    • Your doctor will give you the shot.
    Downsides and risks
    TestopelAveed
    • Not available in generic form, so it can be more expensive.
    • Your doctor has to calculate your dose for 3 months. If it ends up being too much, the doctor might have to remove some of the implant pellets.
    • The pellets can come out, although this is extremely rare.
    • Your doctor has to give you this shot. You can't do it at home.
    • Your doctor has to watch you for 30 minutes after your shot to make sure you don't have problems breathing or get a severe allergic reaction.
    • Your doctor has to file paperwork each time you get the shot because of the risks involved.
    • Not available as a generic, so it can be expensive.
    Tips from our pharmacists for people taking the medication
    TestopelAveed
    • Your doctor will give this you as a shot underneath your skin every 3 months.
    • Can cause nausea, vomiting and headache.
    • Can cause increased acne and changes in sex drive.
    • This medication is only available through a special screening program because of the side effects.
    • Your doctor will watch you for 30 minutes after each injection to make sure you don't have problems breathing or get an allergic reaction.
    • Can cause nausea, vomiting and headache.
    • Can cause increased acne and changes in sex drive.
    Learn more
    More about TestopelSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Testopel (testosterone implant)?
    Worth itNot sureNot worth it
    More about AveedSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Aveed (testosterone undecanoate injection)?
    Worth itNot sureNot worth it