Compare Testopel vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats low testosterone.

The testosterone implant is a good option for long-term testosterone therapy, but it can be expensive, and it's really important that you get the right dose so your doctor doesn't have to remove pellets.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

3.0/ 5 average rating with 100 reviewsforDepo-Testosterone
Upsides
  • Your doctor will give this shot to you every 3 months, so you don't have to worry about administering it yourself like some testosterone injections.
  • Unlike topical forms of testosterone, you don't have to worry about accidentally transferring this medication to another person's skin.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides
  • Not available in generic form, so it can be more expensive.
  • Your doctor has to calculate your dose for 3 months. If it ends up being too much, the doctor might have to remove some of the implant pellets.
  • The pellets can come out, although this is extremely rare.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
Used for
  • Low testosterone
  • Delayed puberty
  • Low testosterone
Dosage forms
  • Implant pellet
  • Injection
Price
No pricing information available
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Reviews
Not enough review data.Leave a review
100 reviews so far
49%
saidit'sworth it
32%
saiditworked well
17%
saidit'sa big hassle

Have you used Depo-Testosterone (Testosterone Cypionate Injection)?

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Side effects
The Testopel (Testosterone Implant) FDA package insert doesn’t have numbers about how common side effects are.
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
No information currently available
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • High calcium in the blood
    • Inability to move
    • Cancer
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings