Compare Theraflu Daytime Severe Cold And Cough vs. Advil Congestion Relief

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Theraflu Daytime Severe Cold And Cough
(acetaminophen / dextromethorphan / phenylephrine)

Advil Congestion Relief
(ibuprofen / phenylephrine)

Relieves cold and flu symptoms. Theraflu Daytime Severe Cold And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is good for treating multiple cold and flu symptoms, but it's more medicine than you need if you only have one symptom.Relieves pain and congestion. Advil Congestion Relief (Ibuprofen / Phenylephrine) is a good combination medicine to relieve pain and congestion, but it's more medicine than you need if you only have one symptom.
Reviews & ratings
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Have you used Theraflu Daytime Severe Cold And Cough (acetaminophen / dextromethorphan / phenylephrine)?
Worth itNot sureNot worth it
Reviews for Advil Congestion Relief
73%
-6% worse vs. Theraflu Daytime Severe Cold And Cough
32%
+1% better vs. Theraflu Daytime Severe Cold And Cough
7%
-10% worse vs. Theraflu Daytime Severe Cold And Cough
1125 reviews
Have you used Advil Congestion Relief (ibuprofen / phenylephrine)?
Worth itNot sureNot worth it
Side effects
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief

We haven’t found good data for Theraflu Daytime Severe Cold And Cough side effects.

FDA side effect reports for Theraflu Daytime Severe Cold And Cough »

We haven’t found good data for Advil Congestion Relief side effects.

FDA side effect reports for Advil Congestion Relief »
How it works
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
Theraflu Daytime Severe Cold And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that treats cold and flu symptoms. Acetaminophen relieves pain and reduces fever. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant that clears your sinuses.Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Ibuprofen is an NSAID that relieves swelling, pain, and fever. Phenylephrine is a decongestant that clears your sinuses.
Type of medication
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
Over-the-counterOver-the-counter
Available as
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • Powder
  • Pill
Used for
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
Risk factors for serious side effects
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • Drinking more than 3 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of chronic obstructive pulmonary disease (COPD)
  • History of smoking
Detailed Theraflu Daytime Severe Cold And Cough (acetaminophen / dextromethorphan / phenylephrine) risks & warnings »
  • History of stomach bleeding or ulcers
  • Age 60 years or older
  • Taking aspirin, NSAIDs, or blood thinners
  • Drinking more than 3 alcoholic beverages a day
  • Women of childbearing age
Detailed Advil Congestion Relief (ibuprofen / phenylephrine) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Interactions
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
No interactions related info.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
Food
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • Theraflu Daytime Severe Cold And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) contains aspartame (phenylalanine). People who have phenylketonuria (PKU) can't break down the amino acid phenylalanine. It builds up and causes serious medical problems. If you have PKU, don't use this product.
No food related info.
Kidneys and liver
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) contains ibuprofen, an NSAID that can lower kidney function or cause damage. Taking the lowest dose for the shortest amount of time lowers your risk. Your doctor should check your kidney function if you take Advil Congestion Relief (Ibuprofen / Phenylephrine) for any amount of time.
Pain
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
No pain related info.
Upsides and benefits
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • Theraflu Daytime Severe Cold And Cough (Acetaminophen / Dextromethorphan / Phenylephrine) is a combination medicine that relieves multiple cold and flu symptoms. It's good to use if you have a stuffy nose, a cough, fever, and pain.
  • Since you're taking this with water, it can help you stay hydrated.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
  • Advil Congestion Relief (Ibuprofen / Phenylephrine) is a combination medicine that relieves multiple cold and allergy symptoms. It's good to use if you have a stuffy nose, sinus pressure, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
Downsides and risks
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
  • If you don't really need both of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • The pain reliever (ibuprofen) can interact with other medications and make health problems like stomach bleeding and ulcers worse.
  • It's not safe to take ibuprofen if you're pregnant since it increases the risk of heart defects in babies.
Tips from our pharmacists for people taking the medication
Theraflu Daytime Severe Cold And CoughAdvil Congestion Relief
  • Starts working in about 30 minutes.
  • Dissolve 1 packet in a cup of hot water and use every 4 hours as needed. Don't use more than 5 packets in 24 hours.
  • Phenylephrine, the decongestant, can make you restless, so don't take it too close to bedtime.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Starts working in 30 minutes.
  • Don't take it if you have an allergy to aspirin since ibuprofen can cause a similar reaction.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Follow age-specific dosing instructions on how much to take. Don't take more than what's recommended on the package.
  • Let your doctor know if your symptoms don't improve in a few days.
Learn more
More about Theraflu Daytime Severe Cold And CoughSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Theraflu Daytime Severe Cold And Cough (acetaminophen / dextromethorphan / phenylephrine)?
Worth itNot sureNot worth it
More about Advil Congestion ReliefSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Advil Congestion Relief (ibuprofen / phenylephrine)?
Worth itNot sureNot worth it