Compare thiothixene vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Navane
(thiothixene)

Abilify
(aripiprazole)

Treats schizophrenia. Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.Helps control your thoughts and mood. Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.
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Coupons for thiothixene
Best available price for 30 (5mg) capsules of thiothixene
Coupons for Abilify
Best available price for 30 (5mg) tablets of abilify
Reviews & ratings
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Have you used Navane (thiothixene)?
Worth itNot sureNot worth it
Reviews for Abilify
44%
-44% worse vs. thiothixene
40%
-40% worse vs. thiothixene
34%
+34% better vs. thiothixene
252 reviews
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it
Side effects
thiothixeneAbilify

The thiothixene FDA package insert doesn’t have numbers about how common side effects are.

More about thiothixene side effects »
  • Sleepiness 20%
  • Difficulty controlling movements 17%
  • Fatigue 7%
  • Nausea 7%
  • Restlessness 8%
  • Blurred vision 8%
  • Excess drooling 6%
  • Dizziness 4%
  • Extreme restlessness 21%
  • Sleep difficulty 6%
More Abilify side effects »
How it works
thiothixeneAbilify
Navane (thiothixene) is a typical antipsychotic. It works by lowering levels of dopamine in the brain. It's believed that schizophrenia might be caused by the brain being too sensitive to changes in dopamine.Abilify (aripiprazole) is an atypical antipsychotic. It stabilizes dopamine and serotonin levels in your brain to help control your thoughts and affect mood.
Type of medication
thiothixeneAbilify
Prescription onlyPrescription only
Available as
thiothixeneAbilify
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Used for
thiothixeneAbilify
Risk factors for serious side effects
thiothixeneAbilify
  • People age 65 or older with dementia and psychosis
  • Drinking alcohol, or taking opioids, benzodiazepines, or sleeping medicines
Detailed Navane (thiothixene) risks & warnings »
  • Elderly patients with dementia
  • Age 24 years or younger
  • Use of antidepressant medications
  • People with diabetes
  • People with high cholesterol
Detailed Abilify (aripiprazole) risks & warnings »
Pregnancy

The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

Alcohol
thiothixeneAbilify
  • Don't drink alcohol while taking Navane (thiothixene).
No alcohol related info.
Food
thiothixeneAbilify
  • Take Navane (thiothixene) with food so you don't get an upset stomach.
No food related info.
Sleep
thiothixeneAbilify
  • Navane (thiothixene) can make you sleepy and unable to focus, so don't drive or do anything requiring concentration for a few hours after taking it until you know how Navane (thiothixene) affects your concentration. This can be worse if you drink alcohol or take medicines that can make you sleepy, such as opioids for pain, benzodiazepines for anxiety, or medicines to help you sleep.
No sleep related info.
Weight
thiothixeneAbilify
  • Side effects include weight gain and high blood sugar.
  • Abilify (aripiprazole) can make you gain weight, which can also increase your blood sugar and cholesterol. If you're at risk for diabetes, high blood pressure or high cholestetrol, talk to your doctor how to lower your risk.
Upsides and benefits
thiothixeneAbilify
  • Navane (thiothixene) is available in generic.
  • Navane (thiothixene) is less likely to make you sleepy.
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
Downsides and risks
thiothixeneAbilify
  • Side effects include weight gain and high blood sugar.
  • Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
  • Smoking tobacco can make Navane (thiothixene) work poorly.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
Tips from our pharmacists for people taking the medication
thiothixeneAbilify
  • Don't drive or do anything requiring concentration until you know how Navane (thiothixene) affects you.
  • You might not notice any changes in your behavior until you've taken Navane (thiothixene) for at least 4 weeks.
  • Navane (thiothixene) can cause low blood pressure. Be very careful getting up if you've been sitting or lying down for a while since you can feel faint.
  • Navane (thiothixene) can make it hard to control your body temperature. Be careful exercising, especially in the heat, and dress warmly if it's cold.
  • Take Navane (thiothixene) with food so you don't get an upset stomach.
  • Don't drink alcohol while taking Navane (thiothixene).
  • Takes 4 to 6 weeks to see full effects on thoughts and mood.
  • Makes you energized. Take in the morning to avoid difficulty sleeping.
  • For the first week, avoid activities that require you to be alert.
  • May increase cholesterol or blood sugar.
  • Report any unusual thoughts, inability to control muscle movements, or fever and excess sweating to your doctor.
  • Available in pills that you take daily, and as a monthly injection.
Learn more
More about thiothixeneSide effectsAlternativesFDA package insert
Have you used Navane (thiothixene)?
Worth itNot sureNot worth it
More about AbilifySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Abilify (aripiprazole)?
Worth itNot sureNot worth it