Compare thiothixene vs. thioridazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Navane (thiothixene)

Prescription only

Mellaril (thioridazine)

Prescription only
Treats schizophrenia.

Navane (thiothixene) isn't a first choice for treating schizophrenia because of the side effects, but it is cheaper than other medicines.

Treats schizophrenia.

Taking Mellaril (thioridazine) is one of many options to treat schizophrenia if other medicines haven't worked, but there are some side effects which can be dangerous.

Upsides
  • Navane (thiothixene) is available in generic.
  • Navane (thiothixene) is less likely to make you sleepy.
  • Available in generic.
  • Compared to other similar medicines, Mellaril (thioridazine) is less likely to cause problems controlling your movements.
Downsides
  • Side effects include weight gain and high blood sugar.
  • Navane (thiothixene) can cause low blood pressure, which can cause fainting or falls if you’re not careful.
  • Smoking tobacco can make Navane (thiothixene) work poorly.
  • Mellaril (thioridazine) is only recommended for schizophrenia if other medicines haven't worked because the side effects can be very dangerous.
  • You have to take Mellaril (thioridazine) numerous times a day which can make it hard to remember.
  • Mellaril (thioridazine) can interfere with your heartbeat, so your doctor might have you do annual tests with your heart to make sure it's healthy.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$25.87
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Lowest price near you
$23.72
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Reviews
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Side effects
The Navane (thiothixene) FDA package insert doesn’t have numbers about how common side effects are.
The Mellaril (thioridazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Higher risk of death

    People age 65 or older with dementia and psychosis

  • Drowsiness and sleepiness

    Drinking alcohol, or taking opioids, benzodiazepines, or sleeping medicines

See more detailed risks and warnings
  • Problems with the heartbeat

    History of heartbeat problems

    ...and 2 more risk factors

  • Increased risk of death in elderly people with dementia

    People older than 65 years with dementia and psychosis

  • Difficulty controlling movements

    Long-term use of Mellaril (thioridazine)

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Sleepiness and risk of falls

    Drinking alcohol or taking narcotics

  • Decreased white blood cells

    History of low white blood cells

See more detailed risks and warnings