Compare tolcapone vs. Emsam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tasmar
(tolcapone)

Eldepryl
(selegiline)

Treats Parkinson's disease. Taking Tasmar (tolcapone) is the next step to control Parkinson's disease when carbidopa/levodopa don't work as well, however you might be more likely to have liver damage.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for
Prices and coupon for 60 (100mg) tablets of tolcapone
Coupons for
Prices and coupon for 60 (5mg) tablets of selegiline
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Tasmar (tolcapone)?
Worth itNot sureNot worth it

Not enough reviews for this drug. Help someone out, leave a review!

Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it
Side effects
tolcaponeEmsam
  • Difficulty controlling movement 22%
  • Nausea 12%
  • Sleeping problems 6%
  • Excessive dreaming 4%
  • Muscle cramps 2%
  • Loss of appetite 6%
  • Sleepiness 5%
  • Lightheadedness from standing 3%
  • Diarrhea 8%
More tolcapone side effects »

We haven’t found good data for Emsam side effects.

FDA side effect reports for Emsam »
How it works
tolcaponeEmsam
Tasmar (tolcapone) is an enzyme inhibitor that stops levodopa from being broken down. It causes higher levodopa in the brain, which relieves the symptoms of Parkinson's disease.Coming soon.
Type of medication
tolcaponeEmsam
Prescription only
Available as
tolcaponeEmsam
  • Pill
  • Pill
  • Patch
Used for
tolcaponeEmsam
  • Major Depressive Disorder
Risk factors for serious side effects
tolcaponeEmsam
  • Liver damage
  • Taking other medicines for Parkinson's disease
    • Taking antipsychotic medicines
      • Taking other medicines for Parkinson's disease
      Detailed Tasmar (tolcapone) risks & warnings »
      Coming soon.
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      tolcaponeEmsam
      • Tasmar (tolcapone) can be taken with or without food.
      No food related info.
      Upsides and benefits
      tolcaponeEmsam
      • Tasmar (tolcapone) is part of the medicines used as the most common next step to control Parkinson's disease when carbidopa/levodopa doesn't work as well.
      • Tasmar (tolcapone) is available as a generic.
      • Tasmar (tolcapone) can be taken with or without food.
      Coming soon
      Downsides and risks
      tolcaponeEmsam
      • When you first start taking Tasmar (tolcapone), your doctor might have to change the dose a lot because of all the side effects.
      • Tasmar (tolcapone) will only slow the disease down; it is not a cure for Parkinson's disease.
      • Unlike Comtan, Tasmar (tolcapone) is more likely to damage your liver, so you might need regular blood tests for the first few months.
      • Tasmar (tolcapone) is not available as a combination pill with carbidopa/levodopa, unlike Comtan.
      • Tasmar (tolcapone) can cause dry mouth and changes in blood pressure. Changes in blood pressure can make you feel faint and more likely to fall.
      Coming soon
      Tips from our pharmacists for people taking the medication
      tolcaponeEmsam
      • Tasmar (tolcapone) can make you dizzy if you've been sitting or lying down for a while. Be very careful when getting up.
      • Don't drive or do anything requiring concentration until you know how Tasmar (tolcapone) affects you.
      • Your urine might be colored dark orange or brown while taking Tasmar (tolcapone). This is normal.
      • You have to keep taking carbidopa/levodopa with Tasmar (tolcapone). Tasmar (tolcapone) won't work by itself to control your Parkinson's disease.
      • Talk to your doctor if you want to stop taking Tasmar (tolcapone). Stopping it suddenly can be very dangerous.
      Coming soon
      Learn more
      More about tolcaponeSide effectsAlternativesFDA package insert
      Have you used Tasmar (tolcapone)?
      Worth itNot sureNot worth it
      More about EmsamSide effectsReviews & ratingsFDA package insert
      Have you used Eldepryl (selegiline)?
      Worth itNot sureNot worth it