Compare Topamax vs. Keppra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Qudexy Xr (Topiramate)

Prescription only

Keppra (Levetiracetam)

Prescription only
Prevents seizures and migraine headaches.

Qudexy Xr (Topiramate) is useful for preventing seizures and migraines, and doesn't require blood tests while you're on it.

4.4/ 7 average rating with 56 reviewsforTopamax
Prevents seizures.

Keppra (Levetiracetam) is effective for preventing seizures in people with epilepsy. Compared to other anti-seizure medications, it has few drug interactions and you don’t need to get your levels checked.

6.2/ 7 average rating with 21 reviewsforKeppra
Upsides
  • Used on its own or with other antiepileptic medicines to lower the frequency of seizures, especially for people with tonic-clonic or partial seizures, or Lennox-Gestaut syndrome.
  • Helpful in preventing frequent migraine headaches.
  • Doesn't need routine blood tests.
  • Lowers the frequency of seizures, including partial-onset, generalized tonic-clonic, and myoclonic seizures.
  • Unlike many other medications for epilepsy, this has very few drug interactions, so your other medicines shouldn't be affected.
  • If you have trouble swallowing tablets, Keppra (Levetiracetam) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
Downsides
  • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
  • A few people will get kidney stones.
  • Not safe to use if you're pregnant.
  • It’s important to take your dose on time so that Keppra (Levetiracetam) has consistent levels in your body.
  • May not be the best drug to take if you have a history of psychiatric issues, such as depression or bipolar disorder.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Keppra (Levetiracetam) is only FDA-approved to be taken with other medicines to treat epilepsy.
Used for
Dosage forms
  • Pill
  • Extended release capsule
  • Pill
  • Extended release
  • Liquid
Price
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$10.2
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$14.75
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Reviews
56 
52%
think this treatment is worth it
50%
think this treatment works well
36%
think this treatment is a hassle

Have you used Qudexy Xr (Topiramate)?

Leave a review
21 
33%
think this treatment is worth it
81%
think this treatment works well
33%
think this treatment is a hassle

Have you used Keppra (Levetiracetam)?

Leave a review
Side effects
10possible side effects
  • Somnolence
    28%
  • Dizziness
    25%
  • Ataxia
    16%
  • Nervousness
    16%
  • Fatigue
    15%
  • Speech disorders/Related speech problems
    13%
  • Psychomotor slowing
    13%
  • Vision abnormal
    13%
  • Difficulty with memory
    12%
  • Paresthesia
    11%
See more detailed side effects
9possible side effects
  • Somnolence
    12%
  • Neck pain
    8%
  • Any side effect
    8%
  • Pharyngitis
    7%
  • Vertigo
    5%
  • Influenza
    5%
  • Depression
    5%
  • Anxiety
    3%
  • Depressed mood
    2%
See more detailed side effects
Risks and warnings
  • Suicidal thoughts or behavior

    History of depression

  • Uncontrolled body temperature

    Children

  • Mental changes due to high ammonia

    History of metabolic disorders

    ...and 1 more risk factors

  • Kidney stones

    Low-carb diet

    ...and 2 more risk factors

  • Withdrawal seizures

    Stopping Qudexy Xr (Topiramate) suddenly

See more detailed risks and warnings
  • Suicidal thoughts or behavior

    History of depression

  • Driving impairment

    Starting the first month of therapy

    ...and 2 more risk factors

  • Withdrawal seizures

    Stopping Keppra (Levetiracetam) suddenly

  • Psychiatric side effects

    History of psychiatric problems

    ...and 1 more risk factors

See more detailed risks and warnings