Compare Topamax vs. Neurontin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Qudexy Xr (Topiramate)

Prescription only

Neurontin (gabapentin)

Prescription only
Prevents seizures and migraine headaches.

Qudexy Xr (Topiramate) is useful for preventing seizures and migraines, and doesn't require blood tests while you're on it.

4.4/ 7 average rating with 56 reviewsforTopamax
Treats tingling and burning nerve pain.

Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.

4.6/ 7 average rating with 620 reviewsforNeurontin
Upsides
  • Used on its own or with other antiepileptic medicines to lower the frequency of seizures, especially for people with tonic-clonic or partial seizures, or Lennox-Gestaut syndrome.
  • Helpful in preventing frequent migraine headaches.
  • Doesn't need routine blood tests.
  • Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
  • Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
  • It's available as a generic, so it's less expensive than similar medications.
Downsides
  • Can cause sleepiness, speech problems, tingling sensations, and weight loss.
  • A few people will get kidney stones.
  • Not safe to use if you're pregnant.
  • Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
  • You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
Used for
Dosage forms
  • Pill
  • Extended release capsule
  • Pill
  • Oral solution
  • Extended release
Price
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$10.2
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$12.05
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Reviews
56 
52%
think this treatment is worth it
50%
think this treatment works well
36%
think this treatment is a hassle

Have you used Qudexy Xr (Topiramate)?

Leave a review
620 
57%
think this treatment is worth it
40%
think this treatment works well
19%
think this treatment is a hassle

Have you used Neurontin (gabapentin)?

Leave a review
Side effects
10possible side effects
  • Somnolence
    28%
  • Dizziness
    25%
  • Ataxia
    16%
  • Nervousness
    16%
  • Fatigue
    15%
  • Speech disorders/Related speech problems
    13%
  • Psychomotor slowing
    13%
  • Vision abnormal
    13%
  • Difficulty with memory
    12%
  • Paresthesia
    11%
See more detailed side effects
The Neurontin (gabapentin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Suicidal thoughts or behavior

    History of depression

  • Uncontrolled body temperature

    Children

  • Mental changes due to high ammonia

    History of metabolic disorders

    ...and 1 more risk factors

  • Kidney stones

    Low-carb diet

    ...and 2 more risk factors

  • Withdrawal seizures

    Stopping Qudexy Xr (Topiramate) suddenly

See more detailed risks and warnings
  • Neurologic and psychiatric side effects (children)

    Children ages 3 to 12

  • Driving impairment

    Taking Neurontin (gabapentin) with alcohol

    ...and 1 more risk factors

  • Withdrawal seizures

    Stopping Neurontin (gabapentin) suddenly

See more detailed risks and warnings