Compare Toprol XL vs. Bisoprolol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zebeta (Bisoprolol)

Prescription only
Lowers blood pressure and controls heart rate.

Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.

3.8/ 5 average rating with 164 reviewsforToprol XL
Lowers blood pressure.

Zebeta (Bisoprolol) is usually given to people who have taken other blood pressure meds unsuccessfully or have recently had significant heart problems.

4.0/ 5 average rating with 18 reviewsforBisoprolol
Upsides
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
  • Good for protecting the heart and lowering blood pressure if you've had a heart attack.
  • Available in a generic version.
  • Also comes in combination with other medications to lower blood pressure.
Downsides
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
  • This isn't a first choice medication to lower blood pressure.
  • You can't stop taking it suddenly, or else you're more likely to have a heart attack or other problems with your heart.
Used for
Dosage forms
  • Extended release
  • Pill
Price
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Reviews
164 reviews so far
60%
saidit'sworth it
54%
saiditworked well
13%
saidit'sa big hassle

Have you used Toprol XL (metoprolol succinate)?

Leave a review
18 reviews so far
67%
saidit'sworth it
61%
saiditworked well
28%
saidit'sa big hassle

Have you used Zebeta (Bisoprolol)?

Leave a review
Side effects
2possible side effects
  • Dizziness/balance problems
    2%
  • Slower heartbeat
    2%
See more detailed side effects
The Zebeta (Bisoprolol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart problems
    • Sudden discontinuation of medicine
    • Coronary artery disease
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
    • Hyperthyroidsim
  • Increased symptoms of heart failure
    • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Trouble breathing (bronchospastic disease)
    • History of asthma
    • History of COPD
See more detailed risks and warnings
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
  • Heart attack
    • Coronary artery disease
  • Increased symptoms of heart failure
    • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
See more detailed risks and warnings