Compare Toprol XL vs. Bystolic

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Lowers blood pressure and controls heart rate.

Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.

3.8/ 5 average rating with 164 reviewsforToprol XL
Lowers blood pressure and controls heart rate.

Bystolic (Nebivolol) is a good blood pressure-lowering medicine for people with heart conditions, and has fewer side effects than other beta blockers, but it's expensive. You can't miss doses.

3.6/ 5 average rating with 154 reviewsforBystolic
Upsides
  • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
  • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
  • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
  • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
  • It's available as a generic and is relatively cheap.
  • Controls your heart rate to reduce work for your heart.
  • A first-line treatment for heart failure and heart attack.
  • Helps to lower blood pressure if you can't use first-choice treatments or need additional blood pressure control.
  • Many beta blockers can worsen asthma or cause headaches, but Bystolic usually doesn't because it targets the heart more specifically and causes fewer side effects.
Downsides
  • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
  • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
  • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
  • Not available in less expensive generic form.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You can't miss doses. Stopping Bystolic suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
Used for
Dosage forms
  • Extended release
  • Pill
Price
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Reviews
164 reviews so far
60%
saidit'sworth it
54%
saiditworked well
13%
saidit'sa big hassle

Have you used Toprol XL (metoprolol succinate)?

Leave a review
154 reviews so far
53%
saidit'sworth it
49%
saiditworked well
18%
saidit'sa big hassle

Have you used Bystolic (Nebivolol)?

Leave a review
Side effects
2possible side effects
  • Dizziness/balance problems
    2%
  • Slower heartbeat
    2%
See more detailed side effects
4possible side effects
  • Headache
    9%
  • Diarrhea
    2%
  • Fatigue
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Heart problems
    • Sudden discontinuation of medicine
    • Coronary artery disease
  • Masked symptoms of low blood sugar
    • Diabetes
  • Masked symptoms of overactive thyroid
    • Hyperthyroidsim
  • Increased symptoms of heart failure
    • Heart failure
  • Increased risks during surgery
    • Major surgery requiring anesthesia
  • Trouble breathing (bronchospastic disease)
    • History of asthma
    • History of COPD
See more detailed risks and warnings
  • Heart problems
    • Sudden discontinuation of medicine
  • Trouble breathing (bronchospastic disease)
    • History of asthma
  • Low blood sugar unawareness
    • History of diabetes
  • Low heart rate (bradycardia)
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
See more detailed risks and warnings