Compare Toprol XL vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toprol XL
(metoprolol succinate)

Coreg
(carvedilol)

Lowers blood pressure and controls heart rate. Toprol XL (metoprolol succinate) is good for controlling chest pain, treating heart failure, and heart attack. It has the added benefit of being taken once a day.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
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5.2Toprol XL
Reviews for Toprol XL (metoprolol succinate)
60%
of people (All ages) say Toprol XL (metoprolol succinate) is worth it
54%
say it works well
13%
say it's a big hassle
164 reviews
Have you used Toprol XL (metoprolol succinate)?
Worth itNot sureNot worth it
Reviews for Coreg (carvedilol)
53%
-7% worse vs. Toprol XL (metoprolol succinate)
46%
-8% worse vs. Toprol XL (metoprolol succinate)
18%
-5% worse vs. Toprol XL (metoprolol succinate)
406 reviews
Have you used Coreg (carvedilol)?
Worth itNot sureNot worth it
Side effects
Toprol XLCoreg
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Skin rash and itching 5%
  • Diarrhea 5%
  • Shortness of breath 3%
  • Slower heartbeat 3%
  • Dizziness/balance problems 1%
More Toprol XL side effects »
  • Dizziness 13%
  • Fatigue 2%
  • High blood sugar 4%
  • Diarrhea 6%
  • Weight increase 3%
  • Nausea 4%
  • Abnormally slow heartbeat 8%
  • Low blood pressure 6%
  • Headache 1%
More Coreg side effects »
How it works
Toprol XLCoreg
Toprol XL (metoprolol succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
Toprol XLCoreg
Prescription only
Prescription only
Available as
Toprol XLCoreg
  • Extended release
  • Pill
  • Extended release
Used for
Toprol XLCoreg
Risk factors for serious side effects
Toprol XLCoreg
  • Sudden discontinuation of medicine
  • Coronary artery disease
  • Diabetes
  • Hyperthyroidsim
  • Heart failure
  • Major surgery requiring anesthesia
  • History of asthma
  • History of COPD
Detailed Toprol XL (metoprolol succinate) risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
      • Congestive heart failure
      • Increasing the dose of Coreg (Carvedilol)
      • Diabetes
      • Major surgery requiring anesthesia
        Detailed Coreg (carvedilol) risks & warnings »
        Pregnancy

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

        Food
        Toprol XLCoreg
        No food related info.
        • You have to take Carvedilol with food.
        • Take it with food.
        Upsides and benefits
        Toprol XLCoreg
        • A first-choice treatment to prevent chest pain (angina). It makes attacks less frequent and helps you be more active without having chest pain.
        • Toprol XL (metoprolol succinate) is a first-choice treatment for heart failure since it may prevent long-term heart damage.
        • It's also a first-choice for heart attack treatment since it lowers the risk of death during and after a heart attack.
        • Toprol XL (metoprolol succinate) is the extended release version of metoprolol tartrate and only needs to be taken once a day.
        • It's available as a generic and is relatively cheap.
        • A first-choice treatment to prevent chest pain (angina).
        • A first-choice treatment for heart failure and heart attack.
        • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
        Downsides and risks
        Toprol XLCoreg
        • Taking a beta blocker can make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some this may not go away.
        • It's not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
        • Toprol XL (metoprolol succinate) can hide symptoms of low blood sugar if you have diabetes.
        • You can't miss doses. Stopping Toprol XL (metoprolol succinate) suddenly can cause your blood pressure to go up quickly, which increases your risk of heart attack and stroke.
        • You have to take Carvedilol with food.
        • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
        • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
        • Can hide symptoms of low blood sugar if you're diabetic.
        • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
        Tips from our pharmacists for people taking the medication
        Toprol XLCoreg
        • Toprol XL (metoprolol succinate) cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine and let your doctor know if it hasn't improved.
        • It can make you feel tired or give you headaches.
        • Can hide symptoms of low blood sugar, so be careful taking this if you have diabetes.
        • Don't stop taking this medicine suddenly.
        • This is the extended-release version, but it also comes in an immediate-release form, metoprolol tartrate.
        • Take it with food.
        • Can cause dizziness in the first few days.
        • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
        • Can cause fatigue and erectile dysfunction.
        • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
        • Don't stop taking this medicine suddenly.
        Learn more
        More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Toprol XL (metoprolol succinate)?
        Worth itNot sureNot worth it
        More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Coreg (carvedilol)?
        Worth itNot sureNot worth it