Compare Toprol XL vs. Coreg

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toprol Xl
(Metoprolol Succinate)

Coreg
(Carvedilol)

Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.Lowers blood pressure and controls heart rate. Coreg (Carvedilol) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.2Toprol XL
Reviews for Toprol Xl (Metoprolol Succinate)
60%
of people (All ages) say Toprol Xl (Metoprolol Succinate) is worth it
54%
say it works well
13%
say it's a big hassle
164 reviews
Have you used Toprol Xl (Metoprolol Succinate)?
Worth itNot sureNot worth it
Reviews for Coreg (Carvedilol)
53%
7% vs. Toprol Xl (Metoprolol Succinate)
46%
8% vs. Toprol Xl (Metoprolol Succinate)
18%
5% vs. Toprol Xl (Metoprolol Succinate)
406 reviews
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it
Side effects
Toprol XLCoreg
  • Abnormally slow heartbeat 9%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
  • Leg or ankle swelling 1%
More Coreg side effects »
How it works
Toprol XLCoreg
Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Coreg (Carvedilol) is an alpha and beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
Toprol XLCoreg
Antihypertensive
Beta blocker
Prescription only
Antihypertensive
Beta blocker
Prescription only
Available as
Toprol XLCoreg
  • Pill
  • Extended release
  • Pill
  • Extended release
Used for (click to learn more)
Toprol XLCoreg
Risk factors for serious side effects
Toprol XLCoreg
  • Diabetes
  • Coronary artery disease
  • Heart failure
  • Major surgery requiring anesthesia
  • History of asthma
Detailed risks & warnings »
  • Abrupt discontinuation of Coreg (Carvedilol)
  • Congestive heart failure
  • Increasing the dose of Coreg (Carvedilol)
  • Diabetes
  • Major surgery requiring anesthesia
Detailed risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Food
Toprol XLCoreg
No food related info.
  • You have to take Carvedilol with food.
  • Take it with food.
Upsides and benefits
Toprol XLCoreg
  • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
  • A first-choice treatment for heart failure. May prevent long-term heart damage.
  • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
  • Toprol XL is the extended release version of Lopressor.
  • A first-choice treatment to prevent chest pain (angina).
  • A first-choice treatment for heart failure and heart attack.
  • For people with severe heart failure, Carvedilol lowers the risk of worsening heart failure, hospitalization, and sudden death.
Downsides and risks
Toprol XLCoreg
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
  • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
  • You have to take Carvedilol with food.
  • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
  • You can't miss doses. Stopping Carvedilol suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
  • Can hide symptoms of low blood sugar if you're diabetic.
Tips from our pharmacists for people taking the medication
Toprol XLCoreg
  • Can cause fatigue and headache.
  • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
  • Take it with food.
  • Can cause fatigue and erectile dysfunction.
  • Can cause dizziness in the first few days.
  • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Don't stop taking this medicine suddenly.
Learn more
More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Toprol Xl (Metoprolol Succinate)?
Worth itNot sureNot worth it
More about CoregSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Coreg (Carvedilol)?
Worth itNot sureNot worth it