Compare Toprol XL vs. Lopressor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toprol Xl
(Metoprolol Succinate)

Lopressor
(Metoprolol Tartrate)

Lowers blood pressure and controls heart rate. Toprol Xl (Metoprolol Succinate) is good for controlling chest pain and treating heart failure and heart attack. You can't miss doses.Lowers blood pressure and controls heart rate. Lopressor (Metoprolol Tartrate) is good for controlling chest pain and treating heart failure and heart attack. You have to take it with food, and you can't miss doses.
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Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.2Toprol XL
Reviews for Toprol Xl (Metoprolol Succinate)
60%
of people (All ages) say Toprol Xl (Metoprolol Succinate) is worth it
54%
say it works well
13%
say it's a big hassle
164 reviews
Have you used Toprol Xl (Metoprolol Succinate)?
Worth itNot sureNot worth it
Reviews for Lopressor (Metoprolol Tartrate)
62%
+2% better vs. Toprol Xl (Metoprolol Succinate)
47%
-7% worse vs. Toprol Xl (Metoprolol Succinate)
15%
-2% worse vs. Toprol Xl (Metoprolol Succinate)
464 reviews
Have you used Lopressor (Metoprolol Tartrate)?
Worth itNot sureNot worth it
Side effects
Toprol XLLopressor
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Rash or pruritus 5%
  • Shortness of breath 3%
  • Abnormally slow heartbeat 3%
  • Low blood pressure 4%
  • Heart block 3%
More Toprol XL side effects »
  • Tiredness 10%
  • Dizziness 10%
  • Low mood disorder 5%
  • Diarrhea 5%
  • Itching 5%
  • Shortness of breath 3%
  • Abnormally slow heartbeat 3%
  • Low blood pressure 4%
More Lopressor side effects »
How it works
Toprol XLLopressor
Toprol Xl (Metoprolol Succinate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.Lopressor (Metoprolol Tartrate) is a beta blocker. It lowers blood pressure by slowing heart rate, relaxing blood vessels, and lowering the body's fight-or-flight response.
Type of medication
Toprol XLLopressor
Prescription only
Prescription only
Available as
Toprol XLLopressor
  • Pill
  • Extended release
  • Pill
Used for
Toprol XLLopressor
Risk factors for serious side effects
Toprol XLLopressor
  • Diabetes
    • Coronary artery disease
    • Heart failure
    • Major surgery requiring anesthesia
    • History of asthma
    Detailed Toprol Xl (Metoprolol Succinate) risks & warnings »
    • Diabetes
      • Coronary artery disease
      • Heart failure
      • Major surgery requiring anesthesia
      • History of asthma
      Detailed Lopressor (Metoprolol Tartrate) risks & warnings »
      Pregnancy

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

      Food
      Toprol XLLopressor
      No food related info.
      • Take it with food.
      Upsides and benefits
      Toprol XLLopressor
      • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
      • A first-choice treatment for heart failure. May prevent long-term heart damage.
      • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
      • Toprol XL is the extended release version of Lopressor.
      • A first-choice treatment to prevent chest pain (angina). Makes pain attacks less frequent and makes it easier to be active without having chest pain.
      • A first-choice treatment for heart failure. May prevent long-term heart damage.
      • A first-choice treatment for heart attack. Lowers the risk of death during and after a heart attack.
      Downsides and risks
      Toprol XLLopressor
      • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
      • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease.
      • Can hide symptoms of low blood sugar if you're diabetic.
      • You can't miss doses. Stopping Toprol XL suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
      • Metoprolol tartrate is the immediate release version of Toprol XL. You have to take Metoprolol tartrate with food for it to work best. (On the other hand, you can take Toprol XL any time.)
      • Taking a beta blocker might make you feel more tired or out of breath during exercise or normal daily routines. This gets better for most people, but for some might not go away.
      • Not a first-choice treatment for high blood pressure according to the latest guidelines, except if you have heart failure or heart disease. As a second choice, your doctor might add it to medicines you're already taking if your blood pressure is still too high.
      • Can hide symptoms of low blood sugar if you're diabetic.
      • You can't miss doses. Stopping Metoprolol tartrate suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
      Tips from our pharmacists for people taking the medication
      Toprol XLLopressor
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Can cause fatigue and headache.
      • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
      • Don't stop taking this medicine suddenly.
      • Extended release version. Also comes in immediate release called Lopressor (metoprolol tartrate).
      • Take it with food.
      • Can cause dizziness in the first few days.
      • Check your blood pressure 1 week after starting this medicine, and tell your doctor if it hasn't improved.
      • Can cause fatigue and headache.
      • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
      • Don't stop taking this medicine suddenly.
      • This is the immediate release version. It also comes as an extended release form: Toprol XL (metoprolol succinate).
      Learn more
      More about Toprol XLSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Toprol Xl (Metoprolol Succinate)?
      Worth itNot sureNot worth it
      More about LopressorSide effectsReviews & ratingsAlternativesFDA package insert
      Have you used Lopressor (Metoprolol Tartrate)?
      Worth itNot sureNot worth it