Compare Toujeo vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo
(insulin glargine)

Glucotrol XL
(glipizide)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers blood sugar. Glucotrol XL (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low, so you must always carry some form of sugar with you that can be readily used.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Glucotrol
Best available price for 60 (5mg) tablets of glucotrol
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for Glucotrol
50%
-50% worse vs. Toujeo
32%
-32% worse vs. Toujeo
19%
+19% better vs. Toujeo
332 reviews
Have you used Glucotrol XL (glipizide)?
Worth itNot sureNot worth it
Side effects
ToujeoGlucotrol
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »
  • Dizziness 1%
  • Diarrhea 5%
  • Nervousness 1%
  • Tremor 4%
  • Passing gas 2%
  • Low blood sugar 3%
  • Constipation 3%
  • Nausea 3%
  • Headache 2%
More Glucotrol side effects »
How it works
ToujeoGlucotrol
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Glucotrol XL (glipizide) stimulates your body to release insulin and lower blood sugar.
Type of medication
ToujeoGlucotrol
Prescription onlyPrescription only
Available as
ToujeoGlucotrol
  • Injection
  • Pill
  • Extended release pill
Used for
ToujeoGlucotrol
Risk factors for serious side effects
ToujeoGlucotrol
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
  • Skipping meals or having inconsistent meal times
  • Drinking alcohol
  • Using other blood sugar-lowering medicine
  • People age 60 or older
  • Those with kidney and/or liver problems
Detailed Glucotrol XL (glipizide) risks & warnings »
Pregnancy
Alcohol
ToujeoGlucotrol
No alcohol related info.
  • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
Food
ToujeoGlucotrol
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
Kidneys and liver
ToujeoGlucotrol
No kidneys and liver related info.
  • People with kidney and/or liver problems take a longer time to get rid of Glucotrol XL (glipizide) from their body. They are more sensitive to the effects of low blood sugar that include symptoms such as fast heartbeat, sweating, pale skin, shakiness, confusion and irritability. They need to make sure to carry with them some form of sugar such as hard candies or glucose tablets at all times while they are on this medicine.
  • Can be used in those with kidney problems.
Weight
ToujeoGlucotrol
  • Can cause weight gain like other insulins
  • Can cause mild weight gain of 2 to 3 pounds on average.
Upsides and benefits
ToujeoGlucotrol
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Lowers A1c levels by 1-2%. (A1c is a test that measures your average blood sugars over the past 3 months).
  • Glucotrol XL (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
  • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
  • Can be used in those with kidney problems.
  • Available as a generic form and is relatively cheap.
Downsides and risks
ToujeoGlucotrol
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • While taking Glucotrol XL (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
  • Can cause mild weight gain of 2 to 3 pounds on average.
  • Might lose its effectiveness over time.
  • Needs to be taken 30 minutes before a meal for it to be most effective.
Tips from our pharmacists for people taking the medication
ToujeoGlucotrol
  • Can be kept at room temperature for 28 days.
  • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
  • Do not mix with any other types of insulin.
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Do not reuse or share pen needles.
  • Take the medicine 30 minutes before eating, usually before your first big meal of the day.
  • Avoid drinking alcohol while taking Glucotrol XL (glipizide).
  • Eat regular and well-balanced meals to keep your blood sugar levels normal.
  • Check your blood sugar regularly.
  • Glucotrol XL (glipizide) can cause dizziness so avoid activities that require coordination until you know how your body can handle the medicine.
Learn more
More about ToujeoSide effectsAlternativesFDA package insert
Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
More about GlucotrolSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Glucotrol XL (glipizide)?
Worth itNot sureNot worth it