Compare Toujeo vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo
(insulin glargine)

Diabeta
(glyburide)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers blood sugar. Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
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Coupons for glyburide
Best available price for 60 (5mg) tablets of glyburide
Reviews & ratings
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Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for glyburide
45%
-45% worse vs. Toujeo
34%
-34% worse vs. Toujeo
21%
+21% better vs. Toujeo
110 reviews
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it
Side effects
Toujeoglyburide
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »
  • Nausea and heartburn 2%
  • Skin allergies 2%
More glyburide side effects »
How it works
Toujeoglyburide
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Diabeta (glyburide) stimulates your body to release insulin and lower blood sugar.
Type of medication
Toujeoglyburide
Prescription onlyPrescription only
Available as
Toujeoglyburide
  • Injection
  • Pill
Used for
Toujeoglyburide
Risk factors for serious side effects
Toujeoglyburide
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
  • Over age 65
  • Kidney problems
  • Use of other blood sugar lowering medicines
  • Alcohol
  • Intense physical activity
Detailed Diabeta (glyburide) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Alcohol
Toujeoglyburide
No alcohol related info.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Food
Toujeoglyburide
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Eat well-balanced meals to avoid low blood sugar.
Kidneys and liver
Toujeoglyburide
No kidneys and liver related info.
  • Not ideal for elderly or those with poor kidney function.
Weight
Toujeoglyburide
  • Can cause weight gain like other insulins
  • Can cause weight gain, dizziness, or stomach upset.
  • Can cause weight gain (about 2 to 3 pounds).
Upsides and benefits
Toujeoglyburide
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides and risks
Toujeoglyburide
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Tips from our pharmacists for people taking the medication
Toujeoglyburide
  • Can be kept at room temperature for 28 days.
  • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
  • Do not mix with any other types of insulin.
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Do not reuse or share pen needles.
  • Check your blood sugar regularly.
  • Eat well-balanced meals to avoid low blood sugar.
  • Works best if you take it 30 minutes before first main meal of the day.
  • Can cause weight gain, dizziness, or stomach upset.
  • Try to avoid drinking alcohol while on Diabeta (glyburide).
Learn more
More about ToujeoSide effectsAlternativesFDA package insert
Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
More about glyburideSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Diabeta (glyburide)?
Worth itNot sureNot worth it