Compare Toujeo vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo (insulin glargine)

Prescription only

Diabeta (glyburide)

Prescription only
Lowers blood sugar.

Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

4.4/ 7 average rating with 110 reviewsforglyburide
Upsides
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
Downsides
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Used for
Dosage forms
  • Injection
  • Pill
Price
No pricing information available
Lowest price near you
$10
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Reviews
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110 
45%
think this treatment is worth it
34%
think this treatment works well
21%
think this treatment is a hassle

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Side effects
The Toujeo (insulin glargine) FDA package insert doesn’t have numbers about how common side effects are.
The Diabeta (glyburide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Changes in blood sugar levels

    Changes in insulin

    ...and 2 more risk factors

  • Medication errors

    Using more than one insulin at a time

  • Severe allergic reactions

    Allergic reactions to other insulins

  • Fluid accumulation leading to heart failure

    Taking thiazolidinediones in combination with insulin

See more detailed risks and warnings
  • Low blood sugar

    Over age 65

    ...and 4 more risk factors

  • Severe allergic reactions

    History of sulfa allergies

See more detailed risks and warnings