Compare Toujeo vs. Humalog

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo
(insulin glargine)

Humalog
(insulin lispro)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers blood sugar. Humalog is a fast-acting insulin that provides meal-time sugar control. It can cause low blood sugar, so make sure you know what the symptoms are and always have a source of sugar nearby.
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Coupons for Humalog
Best available price for 15 (five 3ml cartridges of 100 units/ml) cartons of humalog
Reviews & ratings
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Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for Humalog
64%
-64% worse vs. Toujeo
50%
-50% worse vs. Toujeo
16%
+16% better vs. Toujeo
280 reviews
Have you used Humalog (insulin lispro)?
Worth itNot sureNot worth it
Side effects
ToujeoHumalog
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »
  • Flu syndrome 35%
  • Sore throat 33%
  • Headache 30%
  • Inflammation inside the nose 25%
  • Pain 20%
  • Cough increased 17%
  • Infection 14%
  • Accidental injury 9%
  • Diarrhea 9%
  • Muscle weakness 7%
More Humalog side effects »
How it works
ToujeoHumalog
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Humalog is a short-acting insulin medicine for diabetes. It acts like the insulin that your body normally makes to process sugars and fats, and it keeps your blood sugar stable after meals.
Type of medication
ToujeoHumalog
Prescription onlyPrescription only
Available as
ToujeoHumalog
  • Injection
  • Injection
Used for
ToujeoHumalog
Risk factors for serious side effects
ToujeoHumalog
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
  • Insulin dose too high
  • Use of other blood sugar lowering medicines
  • Poor injection techniques
  • Unstable kidney functions
  • Unstable liver functions
Detailed Humalog (insulin lispro) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Food
ToujeoHumalog
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Short-acting insulin good for blood sugar control around meal times.
Kidneys and liver
ToujeoHumalog
No kidneys and liver related info.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
Weight
ToujeoHumalog
  • Can cause weight gain like other insulins
  • Can cause weight gain and low blood sugar.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
Upsides and benefits
ToujeoHumalog
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Insulin is the most effective blood sugar-lowering medicine. When used correctly, it'll lower blood sugar every time you use it and prevent the harmful effects of high sugar levels on your organs and blood vessels.
  • Humalog is a fast-acting insulin that provides sugar control after meals.
  • Dose can be easily adjusted to make a customized regimen that's tailored to your body.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Okay to use even if you have liver or kidney problems, unlike most other blood sugar-lowering medicines.
Downsides and risks
ToujeoHumalog
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • You have to take insulin by injection.
  • You have to check your blood sugar multiple times every day, usually before each meal.
  • Likely to cause moderate weight gain (around 4 to 6 pounds).
  • Higher risk of low blood sugar episodes than other kinds of diabetes medicines.
Tips from our pharmacists for people taking the medication
ToujeoHumalog
  • Can be kept at room temperature for 28 days.
  • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
  • Do not mix with any other types of insulin.
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Do not reuse or share pen needles.
  • Short-acting insulin good for blood sugar control around meal times.
  • Take 5 to 10 minutes before a meal. Effects last for 2-4 hours.
  • Can cause weight gain and low blood sugar.
  • Make sure you and your family know the symptoms of low blood sugar: sweating, shakiness, weakness, fast heartbeat, nervousness, headache, blurry vision, trouble thinking clearly, or passing out.
  • Always have a good source of sugar nearby for low blood sugar episodes.
  • Make sure you understand how to give yourself the injections.
  • When mixing with another insulin (such as insulin NPH), draw this insulin into the syringe first.
  • Don't shake the vial. Store unopened vials in the refrigerator. Opened vials are good at room temperature for 28 days.
  • Check your blood sugar levels every day.
Learn more
More about ToujeoSide effectsAlternativesFDA package insert
Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
More about HumalogSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Humalog (insulin lispro)?
Worth itNot sureNot worth it