Compare Toujeo vs. Human Insulin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

(insulin glargine)

(human insulin)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers blood sugar. This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.
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Coupons for Human Insulin
Best available price for 15 (five 3ml kwikpens of 100 units/ml) cartons of humulin-n
Reviews & ratings
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Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for Human Insulin
-67% worse vs. Toujeo
-46% worse vs. Toujeo
+11% better vs. Toujeo
Have you used Humulin (human insulin)?
Worth itNot sureNot worth it
Side effects
ToujeoHuman Insulin
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »

The Human Insulin FDA package insert doesn’t have numbers about how common side effects are.

More about Human Insulin side effects »
How it works
ToujeoHuman Insulin
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Insulin is a hormone normally produced by your pancreas. It helps your body absorb and store sugar and fat from your bloodstream.
Type of medication
ToujeoHuman Insulin
Prescription onlyPrescription only
Available as
ToujeoHuman Insulin
  • Injection
  • Injection
  • Inhaler
Used for
ToujeoHuman Insulin
Risk factors for serious side effects
ToujeoHuman Insulin
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
    Detailed Humulin (human insulin) risks & warnings »

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    ToujeoHuman Insulin
    • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
    No food related info.
    ToujeoHuman Insulin
    • Can cause weight gain like other insulins
    • People on Humulin (Human Insulin) can experience weight gain. Talk to your doctor or dietitian about changing your diet if this bothers you.
    Upsides and benefits
    ToujeoHuman Insulin
    • Most effective medicine for controlling your blood sugar.
    • Can be injected once daily.
    • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
    • Can be used in patients 65 and older.
    • Some types of this medication are available without a prescription.
    • Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
    • Available in different combinations so that you can do one shot or multiple shots a day.
    Downsides and risks
    ToujeoHuman Insulin
    • Has to be injected.
    • Can cause weight gain like other insulins
    • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
    • Has to be taken exactly as directed or it can cause high or low blood sugar.
    • As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
    Tips from our pharmacists for people taking the medication
    ToujeoHuman Insulin
    • Can be kept at room temperature for 28 days.
    • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
    • Do not mix with any other types of insulin.
    • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
    • Do not reuse or share pen needles.
    • Change the location where you give yourself the shot every time.
    • Don't use if the liquid in the vial looks different than normal.
    • Store the unopened vials in the refrigerator. The used vials can be kept at room temperature for up to 28 days.
    • Take the medication exactly how your doctor tells you to.
    • Know the symptoms of low blood sugar.
    Learn more
    More about ToujeoSide effectsAlternativesFDA package insert
    Have you used Toujeo (insulin glargine)?
    Worth itNot sureNot worth it
    More about Human InsulinSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Humulin (human insulin)?
    Worth itNot sureNot worth it