Compare Toujeo vs. Janumet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo
(insulin glargine)

Janumet
(sitagliptin / metformin)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers your blood sugar. Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
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Best available price for 60 (50mg/1000mg) tablets of janumet
Reviews & ratings
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Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for Janumet
46%
-46% worse vs. Toujeo
38%
-38% worse vs. Toujeo
15%
+15% better vs. Toujeo
Have you used Janumet (sitagliptin / metformin)?
Worth itNot sureNot worth it
Side effects
ToujeoJanumet
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »
  • Low blood sugar 15%
  • Diarrhea 4%
  • Ear, nose, or throat infection 1%
  • Headache 3%
More Janumet side effects »
How it works
ToujeoJanumet
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Janumet (sitagliptin / metformin) is a combination of two anti-diabetic medicines. Metformin lowers the amount of sugar your body produces, and sitagliptin enhances the release of insulin.
Type of medication
ToujeoJanumet
Prescription onlyPrescription only
Available as
ToujeoJanumet
  • Injection
  • Pill
  • Extended release
Used for
ToujeoJanumet
Risk factors for serious side effects
ToujeoJanumet
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
  • Kidney problems
  • Liver problems
  • Congestive heart failure
  • Using contrast dye for procedures
  • Surgery
Detailed Janumet (sitagliptin / metformin) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Food
ToujeoJanumet
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Take with food to avoid upset stomach with diarrhea, nausea, and vomiting.
Kidneys and liver
ToujeoJanumet
No kidneys and liver related info.
  • Not appropriate for those with poor kidney function.
Weight
ToujeoJanumet
  • Can cause weight gain like other insulins
No weight related info.
Upsides and benefits
ToujeoJanumet
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • This 2-in-1 combination can lower the number of pills you have to take daily.
  • Lowers A1c (average blood sugar over time) up to 2.5%.
  • Available in extended and immediate release forms to allow better control of your blood sugar.
  • Doesn't increase your appetite unlike other anti-diabetic medicines.
  • Does not cause hypoglycemia or very low blood sugar.
Downsides and risks
ToujeoJanumet
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • Available as brand name only and may be expensive.
  • Metformin component usually causes upset stomach.
  • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
  • Not appropriate for those with poor kidney function.
Tips from our pharmacists for people taking the medication
ToujeoJanumet
  • Can be kept at room temperature for 28 days.
  • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
  • Do not mix with any other types of insulin.
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Do not reuse or share pen needles.
  • Take with food to avoid upset stomach with diarrhea, nausea, and vomiting.
  • May cause headaches and cold-like symptoms.
  • Tell your doctor about any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain.
  • Can be expensive depending on insurance coverage.
  • Check your blood sugar regularly.
Learn more
More about ToujeoSide effectsAlternativesFDA package insert
Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
More about JanumetSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Janumet (sitagliptin / metformin)?
Worth itNot sureNot worth it