Compare Toujeo vs. Januvia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Toujeo
(insulin glargine)

Januvia
(sitagliptin)

Lowers blood sugar. Toujeo (insulin glargine) is a concentrated long-actin insulin that allows you to inject higher doses at lower volume compared to other long-acting insulins like Lantus and Levemir.Lowers your blood sugar. Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
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Best available price for 30 (100mg) tablets of januvia
Reviews & ratings
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Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
Reviews for Januvia
44%
-44% worse vs. Toujeo
34%
-34% worse vs. Toujeo
17%
+17% better vs. Toujeo
143 reviews
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it
Side effects
ToujeoJanuvia
  • Hypoglycemia (low blood sugar) 69%
  • Common cold 13%
  • Lung infection 10%
  • Viral infection of the nose and throat 7%
  • Hypoglycemia (low blood sugar) that requires medical attention 5%
More Toujeo side effects »
  • Common cold 2%
  • Diarrhea 1%
  • Upper respiratory infection 3%
  • Headache 1%
More Januvia side effects »
How it works
ToujeoJanuvia
Toujeo (insulin glargine) is a long-acting insulin that lowers blood sugar in your body.Januvia (sitagliptin) is an anti-diabetic drug that enhances your body's release of insulin.
Type of medication
ToujeoJanuvia
Prescription onlyPrescription only
Available as
ToujeoJanuvia
  • Injection
  • Pill
Used for
ToujeoJanuvia
Risk factors for serious side effects
ToujeoJanuvia
  • Changes in insulin
  • Alcohol
  • Other anti-diabetic medications
  • Using more than one insulin at a time
  • Allergic reactions to other insulins
Detailed Toujeo (insulin glargine) risks & warnings »
  • History of pancreatitis
  • High blood triglyceride levels
  • Gallstones (stones in gallbladder)
  • History of alchoholism
  • Kidney problems
Detailed Januvia (sitagliptin) risks & warnings »
Pregnancy

Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

Food
ToujeoJanuvia
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Take once a day in the morning with or without food.
Kidneys and liver
ToujeoJanuvia
No kidneys and liver related info.
  • Januvia (sitagliptin) can worsen kidney problems. Your doctor may check your kidney function before and during treatment. Your doctor may have to adjust the dose or stop this medicine based on changes in kidney function.
Pain
ToujeoJanuvia
No pain related info.
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
Weight
ToujeoJanuvia
  • Can cause weight gain like other insulins
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
Upsides and benefits
ToujeoJanuvia
  • Most effective medicine for controlling your blood sugar.
  • Can be injected once daily.
  • Contains 3 times as much insulin as other long-acting insulins, which means that you can inject lower fluid volume.
  • Can be used in patients 65 and older.
  • Oral blood sugar-lowering medicine.
  • Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
  • Uses the hormones naturally produced by your body to affect how sugar is processed.
  • It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
Downsides and risks
ToujeoJanuvia
  • Has to be injected.
  • Can cause weight gain like other insulins
  • Can cause low blood sugar (hypoglycemia), especially if you do not take it consistently or have an inconsistent meal and exercise schedule.
  • Lowers A1c (average blood sugar over time) by less than 1%.
  • Available as brand version only.
  • Some people might get frequent cold-like symptoms.
  • Rare but serious side effects include pancreatitis and severe joint pain.
Tips from our pharmacists for people taking the medication
ToujeoJanuvia
  • Can be kept at room temperature for 28 days.
  • Inject at the same time each day, but rotate injection sites to prevent skin irritation or deformity.
  • Do not mix with any other types of insulin.
  • Keep a consistent meal and exercise schedule to prevent any fluctuations in your blood sugar.
  • Do not reuse or share pen needles.
  • Take once a day in the morning with or without food.
  • Can cause headache and cold-like symptoms.
  • Tell your doctor right away if you have severe stomach pain, nausea, and/or vomiting. These are symptoms of pancreatitis.
  • Tell your doctor right away if you are experiencing severe joint pain.
  • Check your blood sugar regularly to check for low blood sugar.
Learn more
More about ToujeoSide effectsAlternativesFDA package insert
Have you used Toujeo (insulin glargine)?
Worth itNot sureNot worth it
More about JanuviaSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Januvia (sitagliptin)?
Worth itNot sureNot worth it