Compare Tradjenta vs. Actos
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Tradjenta (linagliptin) is good add-on medicine for controlling your blood sugar, but may cause body aches.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
- Good add-on medicine if your blood sugars are still not controlled
- Good option if you have bad liver or kidney function.
- Can be taken once daily.
- Does not cause weight gain.
- Does not cause hypoglycemia (low blood sugar) when taken by itself.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
- Not first-choice anti-diabetes medicine because it doesn't lower blood sugar levels as much as others.
- Available as brand only and may be expensive
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
- Back pain9%
- Joint pain8%
- Lung infection8%
- Pain in the limbs5%
- Low blood sugar27%
- Colds and flu13%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Inflammation of pancreas (pancreatitis)
...and 2 more risk factors
- Low blood sugar (hypoglycemia)
...and 3 more risk factors
- Heart failure
- Liver damage
Current liver problems
- Bladder cancer
History of bladder cancer
- Bone fracture