Compare Tradjenta vs. Invokamet

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tradjenta (linagliptin)

Prescription only
Lowers blood sugar.

Tradjenta (linagliptin) is good add-on medicine for controlling your blood sugar, but may cause body aches.

Lowers blood sugar.

Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.

Upsides
  • Good add-on medicine if your blood sugars are still not controlled
  • Good option if you have bad liver or kidney function.
  • Can be taken once daily.
  • Does not cause weight gain.
  • Does not cause hypoglycemia (low blood sugar) when taken by itself.
  • Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
  • Does not cause weight gain unlike other anti-diabetic medicines.
  • Not as likely to cause hypoglycemia (low blood sugar)
Downsides
  • Not first-choice anti-diabetes medicine because it doesn't lower blood sugar levels as much as others.
  • Available as brand only and may be expensive
  • Not a good option if you have worsening kidney function such as those age 65 years and up.
  • May cause increased urination.
  • More likely to cause broken bones and yeast and urinary tract infections.
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price near you
$398.11
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Lowest price near you
$444.76
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Reviews
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Side effects
6possible side effects
  • Back pain
    9%
  • Joint pain
    8%
  • Lung infection
    8%
  • Headache
    6%
  • Cough
    6%
  • Pain in the limbs
    5%
See more detailed side effects
9possible side effects
  • Yeast infection in women
    11%
  • Urinary tract infections
    6%
  • Increased urination
    5%
  • Yeast infection in men
    4%
  • Thirst
    3%
  • Vaginal itching
    2%
  • Constipation
    2%
  • Nausea
    2%
  • Abdominal pain
    2%
See more detailed side effects
Risks and warnings
  • Inflammation of pancreas (pancreatitis)

    Alcoholism

    ...and 2 more risk factors

  • Low blood sugar (hypoglycemia)

    Alcoholism

    ...and 3 more risk factors

See more detailed risks and warnings
  • Acid buildup in the blood

    Kidney problems

    ...and 5 more risk factors

  • Low blood pressure (hypotension)

    Over age 65

    ...and 4 more risk factors

  • Bone fractures

    Low blood pressure

    ...and 1 more risk factors

  • Kidney damage

    History of kidney damage

    ...and 3 more risk factors

  • Genital yeast infection and urinary tract infection

    History of urinary tract infections

    ...and 2 more risk factors

  • Low blood sugars

    Taking other diabetic medications

    ...and 2 more risk factors

See more detailed risks and warnings