Compare tranylcypromine vs. Emsam

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Parnate
(tranylcypromine)

Eldepryl
(selegiline)

Stabilizes your mood. Parnate (tranylcypromine) is not a first choice medicine to treat depression because of its side effects and interactions with other medicines and foods.Coming soon.
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Coupons for tranylcypromine
Best available price for 180 (10mg) tablets of tranylcypromine
Coupons for Emsam
Best available price for 60 (5mg) tablets of selegiline
Reviews & ratings
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Reviews for Parnate (tranylcypromine)
Not enough review data. Review it!
of people (All ages) say Parnate (tranylcypromine) is worth it
Not enough review data. Review it!
say it works well
Not enough review data. Review it!
say it's a big hassle
Have you used Parnate (tranylcypromine)?
Worth itNot sureNot worth it
Reviews for Eldepryl (selegiline)
Not enough review data. Review it!
Same vs. Parnate (tranylcypromine)
Not enough review data. Review it!
Same vs. Parnate (tranylcypromine)
Not enough review data. Review it!
-80% worse vs. Parnate (tranylcypromine)
Have you used Eldepryl (selegiline)?
Worth itNot sureNot worth it
Side effects
tranylcypromineEmsam

The tranylcypromine FDA package insert doesn’t have numbers about how common side effects are.

More about tranylcypromine side effects »

We haven’t found good data for Emsam side effects.

FDA side effect reports for Emsam »
How it works
tranylcypromineEmsam
Parnate (tranylcypromine) is a monoamine oxidase inhibitor. It increases the amount of norepinephrine, dopamine, and serotonin in your body which are believed to regulate mood.Coming soon.
Type of medication
tranylcypromineEmsam
Prescription only
Available as
tranylcypromineEmsam
  • Pill
  • Pill
  • Patch
Used for
tranylcypromineEmsam
  • Major Depressive Disorder
Risk factors for serious side effects
tranylcypromineEmsam
  • People under age 24
  • Eating smoked meats, cheese, soy sauce, and fermented foods
  • Beer or wine
  • Excessive amount of chocolate and caffeine
  • Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
Detailed Parnate (tranylcypromine) risks & warnings »
    Coming soon.
    Pregnancy

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Interactions
    tranylcypromineEmsam
    • Parnate (tranylcypromine) interacts with many medicines that can make you more likely to have side effects, so you'll want to tell your doctor and pharmacist what else you're taking, even the supplements and over-the-counter medicines. Your doctor might have to change how you take your medicines so that you don't get side effects.
    No interactions related info.
    Alcohol
    tranylcypromineEmsam
    • Avoid alcohol and limit the amount of caffeine you take if you take Parnate (tranylcypromine).
    • Eating certain foods or drinking beer or wine while taking Parnate (tranylcypromine) can cause your blood pressure to become dangerously high. Talk to your doctor or go to the emergency room right away if you get a very bad headache, changes in your heart rate, neck stiffness or soreness, or nausea and vomiting.
    No alcohol related info.
    Food
    tranylcypromineEmsam
    • Eating certain foods or drinking beer or wine while taking Parnate (tranylcypromine) can cause your blood pressure to become dangerously high. Talk to your doctor or go to the emergency room right away if you get a very bad headache, changes in your heart rate, neck stiffness or soreness, or nausea and vomiting.
    No food related info.
    Weight
    tranylcypromineEmsam
    • Parnate (tranylcypromine) doesn't cause weight gain.
    No weight related info.
    Upsides and benefits
    tranylcypromineEmsam
    • If other medicines haven't worked to help your depression, Parnate (tranylcypromine) can be a good alternative.
    • Parnate (tranylcypromine) doesn't cause weight gain.
    • Parnate (tranylcypromine) doesn't make you feel sleepy.
    • Parnate (tranylcypromine) is available as generic.
    Coming soon
    Downsides and risks
    tranylcypromineEmsam
    • You have to take Parnate (tranylcypromine) 2 to 3 times a day, which can be inconvenient.
    • If you take Parnate (tranylcypromine) any later than early afternoon, you might have problems sleeping.
    • Not recommended in children under 18 years of age.
    Coming soon
    Tips from our pharmacists for people taking the medication
    tranylcypromineEmsam
    • If you're switching from Parnate (tranylcypromine) to another antidepressant, you have to wait at least 2 weeks after stopping Parnate (tranylcypromine) to safely start the new one.
    • Avoid smoked meats, cheese, soy sauce, and other fermented foods because Parnate (tranylcypromine) can raise your blood pressure.
    • You might not notice any changes in your mood until you've taken Parnate (tranylcypromine) for at least 2 to 4 weeks.
    • Don't stop taking Parnate (tranylcypromine) suddenly without talking to your doctor first.
    • Avoid alcohol and limit the amount of caffeine you take if you take Parnate (tranylcypromine).
    • Take your last daily dose of Parnate (tranylcypromine) in the early afternoon so you don't have problems falling asleep.
    Coming soon
    Learn more
    More about tranylcypromineSide effectsAlternativesFDA package insert
    Have you used Parnate (tranylcypromine)?
    Worth itNot sureNot worth it
    More about EmsamSide effectsReviews & ratingsFDA package insert
    Have you used Eldepryl (selegiline)?
    Worth itNot sureNot worth it