Compare Triamterene vs. Inspra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Dyrenium
(triamterene)

Inspra
(eplerenone)

Coming soon.Helps lower blood pressure and protect the heart in people with heart failure. Inspra (eplerenone) lowers blood pressure and can help remove fluid when it's used with other drugs. It reduces the risk of death in people with heart failure and is usually used when people can't take spironolactone.
Reviews & ratings
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Have you used Dyrenium (triamterene)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Inspra (eplerenone)?
Worth itNot sureNot worth it
Side effects
TriamtereneInspra

We haven’t found good data for Triamterene side effects.

FDA side effect reports for Triamterene »
  • High potassium 1%
  • Abnormal renal function 1%
  • Dizziness 1%
  • Diarrhea 1%
  • Coughing 1%
  • Fatigue 1%
  • Flu-like symptoms 1%
More Inspra side effects »
How it works
TriamtereneInspra
Coming soon.Inspra (eplerenone) is an aldosterone antagonist. It blocks aldosterone (a hormone) and helps your kidneys get rid of excess fluid in your body, which helps lower blood pressure.
Type of medication
TriamtereneInspra
Prescription only
Available as
TriamtereneInspra
  • Pill
  • Pill
Used for
TriamtereneInspra
  • Edema
Risk factors for serious side effects
TriamtereneInspra
    Coming soon.
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
    Detailed Inspra (eplerenone) risks & warnings »
    Pregnancy

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Kidneys and liver
    TriamtereneInspra
    No kidneys and liver related info.
    • Inspra (eplerenone) shouldn't be used by people with bad kidneys since it can hurt your kidneys or cause worse side effects, such as high potassium levels. Your doctor will do frequent blood tests to monitor your kidney function and electrolytes while you're on this drug.
    • Shouldn't be used by people with kidney or liver damage.
    • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
    Upsides and benefits
    TriamtereneInspra
    Coming soon
    • Lowers your blood pressure.
    • It can help remove fluid from your body when it's used with other drugs.
    • Reduces the risk of death in people with heart failure.
    • It can have fewer side effects than spironolactone.
    Downsides and risks
    TriamtereneInspra
    Coming soon
    • Inspra (eplerenone) isn't a first choice medicine for lowering blood pressure or getting rid of fluid in the body. It's usually used in combination with other medicines.
    • It can make you feel dizzy for the first few days. Be careful driving until you know how it affects you.
    • You'll need to have blood tests done regularly since Inspra (eplerenone) can affect your potassium levels and kidney function.
    • It can be very expensive compared to spironolactone.
    Tips from our pharmacists for people taking the medication
    TriamtereneInspra
    Coming soon
    • Inspra (eplerenone) can make you feel dizzy the first few days you're taking it.
    • It can increase your potassium to dangerous levels, so don't use salt substitutes or other products that contain potassium.
    • Women may notice breast tenderness or swelling and irregular periods.
    • Shouldn't be used by people with kidney or liver damage.
    • Your doctor will check the amount of potassium in your blood while you're on this drug.
    Learn more
    More about TriamtereneSide effectsFDA package insert
    Have you used Dyrenium (triamterene)?
    Worth itNot sureNot worth it
    More about InspraSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Inspra (eplerenone)?
    Worth itNot sureNot worth it