Compare trifluoperazine vs. Abilify

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Stelazine (trifluoperazine)

Prescription only

Abilify (aripiprazole)

Prescription only
Treats anxiety and schizophrenia.

Stelazine (trifluoperazine) can be used to treat schizophrenia, but you might have trouble controlling your movements.

Helps control your thoughts and mood.

Abilify (aripiprazole) is good for treating psychosis and mania, and can help with depression. It's less likely to cause side effects than other antipsychotics.

4.3/ 7 average rating with 252 reviewsforAbilify
Upsides
  • Stelazine (trifluoperazine) is one of the recommended medicines for schizophrenia.
  • It’s approved in children age 6 and older.
  • Available in generic.
  • Compared to other similar medicines, you're less likely to feel dehydrated or have problems with your heart with Stelazine (trifluoperazine).
  • Effective at relieving psychotic symptoms and manic episodes.
  • More energizing than other antipsychotics.
  • Fewer side effects than other antipsychotics.
  • Studies show that it can also be helpful for depression, especially in women, if your symptoms don't go away with an antidepressant alone.
  • Available as a generic, which is cheaper.
Downsides
  • If you take Stelazine (trifluoperazine) for more than 12 weeks or are taking high doses of Stelazine (trifluoperazine), you’re at a higher risk for being unable to control your movements.
  • Stelazine (trifluoperazine) can cause agitation and trouble sleeping. These symptoms can sometimes disappear, or there are other treatments you can take to help.
  • Mild risk of extrapyramidal symptoms (EPS), a movement disorder that includes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
  • You might need routine blood tests to check how the medicine is affecting your body.
  • All antipsychotics come with side effects that make them difficult to take. You might need to try a few different medicines until you find the one that works for you and that you can tolerate.
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Liquid
  • Injection
Price
No pricing information available
Lowest price near you
$35.45
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Reviews
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252 
44%
think this treatment is worth it
40%
think this treatment works well
34%
think this treatment is a hassle

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Side effects
The Stelazine (trifluoperazine) FDA package insert doesn’t have numbers about how common side effects are.
The Abilify (aripiprazole) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Higher risk of death in people age 65 and older with dementia

    People age 65 and older with dementia and psychosis

  • Difficulty controlling movements

    Women age 65 and older

  • Neuroleptic malignant syndrome

    Taking antipsychotic medications

  • Changes in blood cell counts

    History of low white or red blood cell counts

See more detailed risks and warnings
  • Increased risk of death

    Elderly patients with dementia

  • Suicidal thoughts or behavior

    Age 24 years or younger

    ...and 1 more risk factors

  • Increased blood sugar and cholesterol, and weight gain

    People with diabetes

    ...and 1 more risk factors

  • Driving impairment

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings