Compare trifluoperazine vs. Geodon

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Geodon (Ziprasidone)

Prescription only
Treats anxiety and schizophrenia.

Stelazine (trifluoperazine) can be used to treat schizophrenia, but you might have trouble controlling your movements.

Helps control your thoughts and mood.

Geodon (Ziprasidone) treats bipolar disorder and schizophrenia, and causes fewer side effects than similar medicines. It’s not a good choice if you have heart problems.

3.4/ 5 average rating with 23 reviewsforGeodon
Upsides
  • Stelazine (trifluoperazine) is one of the recommended medicines for schizophrenia.
  • It’s approved in children age 6 and older.
  • Available in generic.
  • Compared to other similar medicines, you're less likely to feel dehydrated or have problems with your heart with Stelazine (trifluoperazine).
  • Geodon (Ziprasidone) can be used with lithium or valproate to better treat bipolar disorder.
  • Geodon (Ziprasidone) can treat agitation in people with schizophrenia by reducing symptoms of anxiety, nervousness, and distress.
  • Compared to other antipsychotics, it has a lower risk of weight gain, hyperglycemia, and hyperlipidemia.
  • The Geodon (Ziprasidone) capsule is available as a generic.
  • The injectable form can treat sudden agitation in schizophrenia when it's not possible to use the capsules.
  • It's available as a pill that you take by mouth daily for continuous treatment and as an injection used for short-term treatment of agitation.
Downsides
  • If you take Stelazine (trifluoperazine) for more than 12 weeks or are taking high doses of Stelazine (trifluoperazine), you’re at a higher risk for being unable to control your movements.
  • Stelazine (trifluoperazine) can cause agitation and trouble sleeping. These symptoms can sometimes disappear, or there are other treatments you can take to help.
  • Elderly people with dementia shouldn’t take Geodon (Ziprasidone).
  • You shouldn’t take Geodon (Ziprasidone) if you have a history of heart problems (slow heart rate, recent heart attack, heart failure, or heart rhythm problems). It’s also not safe to take if you have low potassium or magnesium, or are taking medicines that increase the risk of this happening (diuretics).
  • You'll need to get blood tests before you start taking Geodon (Ziprasidone).
  • It causes slightly less weight gain than similar medicines.
  • Can't take Geodon (Ziprasidone) capsules and injections at the same time. Capsules should be used instead of the injection as soon as possible.
Used for
Dosage forms
  • Pill
  • Pill
  • Injection
Price
No pricing information available
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Reviews
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23 reviews so far
43%
saidit'sworth it
43%
saiditworked well
30%
saidit'sa big hassle

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Side effects
The Stelazine (trifluoperazine) FDA package insert doesn’t have numbers about how common side effects are.
12possible side effects
  • Injection Site Pain
    9%
  • Somnolence
    8%
  • Nausea
    4%
  • Headache
    3%
  • Diarrhea
    3%
  • Dizziness
    3%
  • Insomnia
    3%
  • Asthenia
    2%
  • Hypertension
    2%
  • Anxiety
    2%
  • Agitation
    2%
  • Extrapyramidal Syndrome
    2%
See more detailed side effects
Risks and risk factors
  • Higher risk of death in people age 65 and older with dementia
    • People age 65 and older with dementia and psychosis
  • Difficulty controlling movements
    • Women age 65 and older
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Changes in blood cell counts
    • History of low white or red blood cell counts
  • Liver damage
  • Low blood pressure and higher risk of falls
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Heart problems
    • History of heart problems
    • Drug interactions
    • Low potassium
    • Low magnesium
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Duration of treatment
  • Low blood pressure
  • Risk to fetus
    • Women of childbearing age
See more detailed risks and warnings