Compare trifluoperazine vs. Zyprexa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zyprexa (olanzapine)

Prescription only
Treats anxiety and schizophrenia.

Stelazine (trifluoperazine) can be used to treat schizophrenia, but you might have trouble controlling your movements.

Helps control your thoughts and mood.

Zyprexa (olanzapine) is good for treating psychosis, mania, and agitation, but it's more likely to cause weight gain and sleepiness than other antipsychotics.

3.7/ 5 average rating with 68 reviewsforZyprexa
Upsides
  • Stelazine (trifluoperazine) is one of the recommended medicines for schizophrenia.
  • It’s approved in children age 6 and older.
  • Available in generic.
  • Compared to other similar medicines, you're less likely to feel dehydrated or have problems with your heart with Stelazine (trifluoperazine).
  • Effective at relieving psychotic symptoms, manic episodes, and agitation in people with schizophrenia and bipolar disorder.
  • Less likely to cause heart problems than other antipsychotics.
  • Less likely to cause movement problems compared to older antipsychotics.
Downsides
  • If you take Stelazine (trifluoperazine) for more than 12 weeks or are taking high doses of Stelazine (trifluoperazine), you’re at a higher risk for being unable to control your movements.
  • Stelazine (trifluoperazine) can cause agitation and trouble sleeping. These symptoms can sometimes disappear, or there are other treatments you can take to help.
  • More likely to cause weight gain and increase cholesterol or blood sugar compared to other antipsychotics.
  • Might make you more sleepy than some antipsychotics.
  • Mild risk of Extrapyramidal Symptoms (EPS): Movement disorders that include stiffness, tremor, restlessness, and slow, repetitive movements you can't control.
  • You may need routine blood tests to check how the medicine is affecting your body..
Used for
Dosage forms
  • Pill
  • Pill
  • Dissolving tablet
  • Injection
Price
No pricing information available
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Reviews
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68 reviews so far
41%
saidit'sworth it
51%
saiditworked well
51%
saidit'sa big hassle

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Side effects
The Stelazine (trifluoperazine) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
  • Drowsiness
    48%
  • Weight gain
    28%
  • Increased appetite
    28%
  • Headache
    17%
  • Fatigue
    14%
  • Dizziness
    7%
  • Dry Mouth
    7%
  • Abdominal pain
    6%
  • Pain in extremity
    5%
See more detailed side effects
Risks and risk factors
  • Higher risk of death in people age 65 and older with dementia
    • People age 65 and older with dementia and psychosis
  • Difficulty controlling movements
    • Women age 65 and older
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Changes in blood cell counts
    • History of low white or red blood cell counts
  • Liver damage
  • Low blood pressure and higher risk of falls
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Higher blood sugar, high cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
See more detailed risks and warnings