Compare Trileptal vs. Keppra

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trileptal (Oxcarbazepine)

Prescription only

Keppra (Levetiracetam)

Prescription only
Prevents seizures.

Trileptal (Oxcarbazepine) is effective at preventing seizures and you don’t need to get regular blood tests to make sure it’s effective, but it has many drug interactions.

Prevents seizures.

Keppra (Levetiracetam) is effective for preventing seizures in people with epilepsy. Compared to other anti-seizure medications, it has few drug interactions and you don’t need to get your levels checked.

4.5/ 5 average rating with 21 reviewsforKeppra
Upsides
  • Trileptal (Oxcarbazepine) is effective at lowering the frequency of seizures, especially for people with partial seizures.
  • If you have trouble swallowing tablets, Trileptal (Oxcarbazepine) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
  • Available in a generic form.
  • Lowers the frequency of seizures, including partial-onset, generalized tonic-clonic, and myoclonic seizures.
  • Unlike many other medications for epilepsy, this has very few drug interactions, so your other medicines shouldn't be affected.
  • If you have trouble swallowing tablets, Keppra (Levetiracetam) is also available as an oral solution.
  • You won’t need to get regular blood tests to check the drug levels in your body.
Downsides
  • It’s important to take your dose on time so that Trileptal (Oxcarbazepine) has steady levels in your body.
  • Interacts with many other medicines and supplements.
  • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Being pregnant lowers the levels of Trileptal (Oxcarbazepine), so the medicine might not be as effective at preventing seizures.
  • It’s important to take your dose on time so that Keppra (Levetiracetam) has consistent levels in your body.
  • May not be the best drug to take if you have a history of psychiatric issues, such as depression or bipolar disorder.
  • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
  • Keppra (Levetiracetam) is only FDA-approved to be taken with other medicines to treat epilepsy.
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Liquid
Price
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Reviews
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21 reviews so far
33%
saidit'sworth it
81%
saiditworked well
33%
saidit'sa big hassle

Have you used Keppra (Levetiracetam)?

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Side effects
21possible side effects
  • Dizziness
    22%
  • Nausea
    16%
  • Headache
    13%
  • Any adverse effect
    9%
  • Diarrhea
    7%
  • Vomiting
    7%
  • Upper Respiratory Tract Infection
    7%
  • Constipation
    5%
  • Dyspepsia
    5%
  • Ataxia
    5%
  • Nervousness
    5%
  • Falling Down NOS
    4%
  • Pain Back
    4%
  • Amnesia
    4%
  • Coordination Abnormal
    4%
  • Tremor
    4%
  • Epistaxis
    4%
  • Infection Chest
    4%
  • Sinusitis
    4%
  • Rash
    4%
  • Vision Abnormal
    4%
See more detailed side effects
14possible side effects
  • Somnolence
    12%
  • Neck pain
    8%
  • Any side effect
    8%
  • Pharyngitis
    7%
  • Vertigo
    5%
  • Influenza
    5%
  • Depression
    5%
  • Anxiety
    3%
  • Depressed mood
    2%
  • Diplopia
    2%
  • Hypersomnia
    2%
  • Insomnia
    2%
  • Irritability
    2%
  • Nervousness
    2%
See more detailed side effects
Risks and risk factors
  • Mental changes due to low sodium
    • Age 65 or older
    • dehydration
    • Taking diuretics (water pills)
  • Serious allergic reactions
    • Had allergic reaction to Tegretol (carbamazepine)
  • Life-threatnening skin reactions
    • Asian ancestry
  • Suicidal thoughts or behavior
    • History of depression
  • Withdrawal seizures
    • Stopping Trileptal (Oxcarbazepine) suddenly
  • Changes in blood cells
  • Bone disorders
    • History of osteoporosis
    • History of fractures
  • Liver problems
  • Low thyroid levels
    • Children
See more detailed risks and warnings
  • Blood disorders
  • Life-threatnening skin reactions
  • Suicidal thoughts or behavior
    • History of depression
  • Driving impairment
    • Starting the first month of therapy
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Withdrawal seizures
    • Stopping Keppra (Levetiracetam) suddenly
  • Psychiatric side effects
    • History of psychiatric problems
    • Ages less than 18
See more detailed risks and warnings