Compare Trileptal vs. Tegretol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trileptal
(Oxcarbazepine)

Tegretol
(Carbamazepine)

Prevents seizures. Trileptal (Oxcarbazepine) is effective at preventing seizures and you don’t need to get regular blood tests to make sure it’s effective, but it has many drug interactions.Prevents seizures, stabilizes mood, and relieves nerve pain. Tegretol (Carbamazepine) is useful for preventing seizures and relieving certain types of nerve pain, but interacts with many drugs.
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Reviews & ratings
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Reviews for Tegretol (Carbamazepine)
58%
+8% vs. Trileptal (Oxcarbazepine)
42%
+17% vs. Trileptal (Oxcarbazepine)
21%
+4% vs. Trileptal (Oxcarbazepine)
Side effects
TrileptalTegretol
  • Dizziness 16%
  • Diarrhea 5%
  • Nausea 4%
  • Nervousness 3%
  • Headache 3%
  • Coordination abnormal 2%
  • Pain back 2%
  • Sinus inflammation 2%
  • Rash 2%
  • Amnesia 2%
More Trileptal side effects »
  • Dizziness 32%
  • Drowsiness 19%
  • Nausea 19%
  • Vomiting 15%
  • Itching 6%
  • Constipation 5%
  • Dry mouth 5%
  • Muscle weakness 4%
  • Blurred vision 4%
  • Rash 3%
More Tegretol side effects »
How it works
TrileptalTegretol
Trileptal (Oxcarbazepine) is an antiepileptic medication. It reduces seizures by blocking certain types of nerve activity that regulate how your brain cells communicate with each other.Tegretol (Carbamazepine) is an antiepileptic. Researchers don't know exactly how it works, but it seems to block certain kinds of nerve activity to reduce seizures and pain.
Type of medication
TrileptalTegretol
AnticonvulsantPrescription only
AnticonvulsantPrescription only
Available as
TrileptalTegretol
  • Pill
  • Liquid
  • Pill
  • Extended release
  • Chewable tablet
  • Oral suspension
Used for (click to learn more)
TrileptalTegretol
Risk factors for serious side effects
TrileptalTegretol
  • Age 65 or older
  • dehydration
  • Taking diuretics (water pills)
  • Had allergic reaction to Tegretol (carbamazepine)
  • Asian ancestry
  • History of depression
  • Stopping Trileptal (Oxcarbazepine) suddenly
    • History of osteoporosis
    • History of fractures
      • Children
      Detailed Trileptal (Oxcarbazepine) risks & warnings »
      • People also taking Depakote
      • Asian ancestry
        • History of depression
        • European, Chinese, or Japanese ancestry
          • Age 65 years or older
          • Stopping Tegretol (Carbamazepine) suddenly
          Detailed Tegretol (Carbamazepine) risks & warnings »
          Pregnancy category
          TrileptalTegretol
          CFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          DFDA pregnancy category (Weigh risks vs. benefits)

          Research studies with real people found harmful effects on unborn babies, but the benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

          See the FDA package insert
          Alcohol
          No specific alcohol-related info.No specific alcohol-related info.
          Food
          • Trileptal (Oxcarbazepine) can be taken with or without food.
          No specific food-related info.
          Kidneys and liver
          • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
          No specific kidneys and liver-related info.
          Sex
          No specific sex-related info.No specific sex-related info.
          Sleep
          • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
          • You can experience dizziness, drowsiness, double vision, stomach upset, and trouble with coordination while on this.
          No specific sleep-related info.
          Weight
          • Hypothyroidism (low thyroid levels) have been reported with Trileptal (Oxcarbazepine). Your thyroid levels may need to be tested regularly, Let your doctor know if you are more fatigued, gaining weight without any apparent reason, feeling more depressed, or are more sensitive to cold.
          No specific weight-related info.
          Upsides and benefits
          TrileptalTegretol
          • Trileptal (Oxcarbazepine) is effective at lowering the frequency of seizures, especially for people with partial seizures.
          • If you have trouble swallowing tablets, Trileptal (Oxcarbazepine) is also available as an oral solution.
          • You won’t need to get regular blood tests to check the drug levels in your body.
          • Available in a generic form.
          • Lowers the frequency of seizures, especially for people with tonic-clonic and partial seizures.
          • First-line option for trigeminal neuralgia (nerve pain involving the face, head, and neck), and can relieve other types of nerve pain.
          • May be helpful in stabilizing mood for people with bipolar disorder.
          Downsides and risks
          TrileptalTegretol
          • It’s important to take your dose on time so that Trileptal (Oxcarbazepine) has steady levels in your body.
          • Can cause difficulty concentrating, tiredness or drowsiness, and problems with coordination.
          • If you have kidney problems, your dose may need to be adjusted. Your doctor will check your kidney function regularly.
          • Being pregnant lowers the levels of Trileptal (Oxcarbazepine), so the medicine might not be as effective at preventing seizures.
          • Interacts with many other medicines and supplements.
          • Higher risk of skin reactions compared to other antiepileptic medicines, ranging from mild to life-threatening rash.
          • Can cause blurry vision, dizziness, and upset stomach.
          • Not safe to use if you're pregnant.
          • Requires routine blood tests to see how the medicine is affecting your body.
          • Interacts with many other medicines and supplements.
          Tips from our pharmacists for people taking the medication
          TrileptalTegretol
          • You can experience dizziness, drowsiness, double vision, stomach upset, and trouble with coordination while on this.
          • If you start having skin rashes or thoughts of suicide, tell your doctor immediately.
          • If you need to stop taking Trileptal (Oxcarbazepine), do so over at least one week to prevent withdrawal seizures.
          • Trileptal (Oxcarbazepine) makes birth control and many other medicines less effective.
          • Trileptal (Oxcarbazepine) can be taken with or without food.
          • If you're taking the oral suspension, use the measuring device given with the medicine. Don’t use your household tablespoons to measure.
          • For the first week, avoid activities that require you to be alert.
          • Report skin rashes or blistering immediately.
          • Don't use if pregnant.
          • Requires routine blood tests.
          • Report confusion, persistent abdominal pain, yellowing of eyes/skin, or easy bruising to your doctor.
          • Takes up to 5 weeks to feel full effects on mood.
          Learn more
          More about TrileptalSide effectsReviews & ratingsAlternativesFDA package insert
          More about TegretolSide effectsReviews & ratingsAlternativesFDA package insert