Compare Trilipix vs. Atorvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trilipix
(fenofibric acid)

Lipitor
(atorvastatin)

Lowers cholesterol. Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.Lowers cholesterol. Lipitor (atorvastatin) improves your cholesterol levels and is a common first treatment for people with high cholesterol or heart disease.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
3.79Trilipix
Reviews for Trilipix
50%
of people (All ages) say Trilipix is worth it
22%
say it works well
25%
say it's a big hassle
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it
Reviews for Atorvastatin
63%
-13% worse vs. Trilipix
51%
-29% worse vs. Trilipix
13%
-12% worse vs. Trilipix
1377 reviews
Have you used Lipitor (atorvastatin)?
Worth itNot sureNot worth it
Side effects
TrilipixAtorvastatin
  • Headache 13%
  • Back Pain 6%
  • Pain in Extremity 5%
  • Upper respiratory tract infection 5%
  • Nausea 4%
  • Nasopharyngitis 4%
  • Diarrhea 4%
  • Arthralgia 4%
  • Pain 4%
  • Dizziness 4%
More Trilipix side effects »
  • Diarrhea 1%
  • Indigestion 1%
  • Muscle Spasms 1%
  • Myalgia 1%
More Atorvastatin side effects »
How it works
TrilipixAtorvastatin
Trilipix is a cholesterol-lowering medicine. It removes triglycerides from your body and makes it easier to process "bad" cholesterol (LDL). This also increases "good" cholesterol (HDL).Lipitor (atorvastatin) is a cholesterol-lowering medicine called a statin. It lowers the amount of cholesterol your body makes, which helps lower "bad" cholesterol (LDL) and raise "good" cholesterol (HDL).
Type of medication
TrilipixAtorvastatin
Prescription onlyPrescription only
Available as
TrilipixAtorvastatin
  • Pill
  • Extended release
  • Pill
Used for
TrilipixAtorvastatin
Risk factors for serious side effects
TrilipixAtorvastatin
  • Taking Trilipix (Fenofibric Acid) with statins
  • Past history of liver disease
  • Taking Trilipix (Fenofibric Acid) with anticoagulants
Detailed Trilipix (fenofibric acid) risks & warnings »
  • Heavy alcohol use
  • Prior history of chronic liver disease
  • Pregnancy
  • History of hemorrhagic strokes
Detailed Lipitor (atorvastatin) risks & warnings »
Pregnancy

Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

Research studies with real people or animals found harmful effects on unborn babies. If you’re pregnant, the risks to your unborn baby outweigh the benefits.

Alcohol
TrilipixAtorvastatin
No alcohol related info.
  • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
Kidneys and liver
TrilipixAtorvastatin
  • Reports of liver damage have been reported in people who take Trilipix (Fenofibric Acid), especially in people with a history of liver disease. Your doctor may monitor your liver with blood tests on a regular basis.
  • People on Lipitor (atorvastatin) have reported muscle pain, which may lead to muscle and kidney damage. This is more likely to happen if you're older and you're taking higher doses of Lipitor (atorvastatin). If you suddenly feel muscle pain or weakness and you haven't been exercising, stop taking Lipitor (atorvastatin) and talk to your doctor right away.
  • Liver damage has been reported in people who take Lipitor (atorvastatin). If you notice dark urine or yellowing of your eyes or skin, talk to your doctor. Your doctor might run blood tests to check your liver.
  • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
  • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
Pain
TrilipixAtorvastatin
No pain related info.
  • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
Upsides and benefits
TrilipixAtorvastatin
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats), and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Lipitor (atorvastatin) can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • It's one of the strongest cholesterol-lowering statin medications.
  • Lipitor (atorvastatin) is a good option for people who have high cholesterol and diabetes.
  • It's available as a generic drug and can be used in combination with other cholesterol lowering drugs.
Downsides and risks
TrilipixAtorvastatin
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
  • Statins such as Lipitor (atorvastatin) can cause digestive problems, blood sugar problems, muscle aches and stiffness, muscle injury, kidney damage, or liver damage. Some people need to stop taking this medicine if these problems occur.
  • You're at higher risk for these side effects if you are a female, are 65 years or older, or drink more than two alcoholic drinks a day, take more than one medicine for cholesterol, or have liver disease, kidney disease, or diabetes.
  • Eating grapefruit or drinking grapefruit juice can raise your risk of liver damage while taking Lipitor (atorvastatin).
Tips from our pharmacists for people taking the medication
TrilipixAtorvastatin
  • Can be used with other medications to help lower cholesterol.
  • Lowers triglycerides.
  • Can raise your chance of getting colds and flu.
  • Call your doctor if you develop muscle or abdominal pain.
  • Also taking Welchol or Questran? Take this medicine at least 2 hours before or 4 hours after.
  • Lowers bad cholesterol and triglycerides, and raises good cholesterol.
  • Don't eat grapefruit or drink grapefruit juice while taking this medicine.
  • Tell your doctor if you suddenly feel severe muscle pain, fever, or weakness.
  • Also tell your doctor if you have dark urine or if you notice a yellow tint in your eyes or skin.
  • Lipitor (atorvastatin) isn't safe to use if you're pregnant.
Learn more
More about TrilipixSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Trilipix (fenofibric acid)?
Worth itNot sureNot worth it
More about AtorvastatinSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Lipitor (atorvastatin)?
Worth itNot sureNot worth it