Compare Trilipix vs. simvastatin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Trilipix (Fenofibric Acid)

Prescription only

Zocor (simvastatin)

Prescription only
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

3.8/ 7 average rating with 68 reviewsforTrilipix
Lowers cholesterol.

Zocor (simvastatin) is a good medication to improve your cholesterol.

5.1/ 7 average rating with 1176 reviewsforsimvastatin
Upsides
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
  • Can lower the risk of heart attack, stroke, and death, particularly if you have diabetes, high blood pressure, obesity, or a history of smoking.
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Available in generic.
  • Available in combination pills with other cholesterol medicines.
Downsides
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
  • You are at higher risk for side effects if you are female, are 65 years or older, drink alcohol every day, or have liver disease, kidney disease, or diabetes.
  • Not safe to use if you're pregnant.
  • Can have more drug interactions than some other drugs in the same class (statins).
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
Lowest price near you
$64.75
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Lowest price near you
$4
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Reviews
68 
50%
think this treatment is worth it
22%
think this treatment works well
25%
think this treatment is a hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
1176 
61%
think this treatment is worth it
48%
think this treatment works well
14%
think this treatment is a hassle

Have you used Zocor (simvastatin)?

Leave a review
Side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
The Zocor (simvastatin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and warnings
  • Muscle pain

    Taking Trilipix (Fenofibric Acid) with statins

  • Liver damage

    Past history of liver disease

  • Increased bleeding risk

    Taking Trilipix (Fenofibric Acid) with anticoagulants

See more detailed risks and warnings
  • Muscle pain and kidney damage

    Kidney disease

    ...and 4 more risk factors

  • Liver damage

    Heavy alcohol use

    ...and 1 more risk factors

  • Harm to unborn baby

    Pregnancy

    ...and 1 more risk factors

  • Drug interactions

    Certain drugs can increase the dose of Zocor (simvastatin) in the body

  • High blood sugar

    History of high blood sugar

See more detailed risks and warnings