Compare Trilipix vs. Zetia

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Zetia (ezetimibe)

Prescription only
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

2.9/ 5 average rating with 68 reviewsforTrilipix
Lowers cholesterol.

Zetia (ezetimibe) can improve your cholesterol and can be used as an alternative to statins.

3.3/ 5 average rating with 128 reviewsforZetia
Upsides
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Can be used with other medicines to improve cholesterol.
  • Available in a combination pill with simvastatin.
  • Available as a generic.
Downsides
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
  • Doesn't lower triglycerides (fats).
  • Hasn't been shown to lower the risk of heart attacks or heart disease.
  • By itself, it isn't as effective as statins for improving cholesterol.
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
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Reviews
68 reviews so far
50%
saidit'sworth it
22%
saiditworked well
25%
saidit'sa big hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
128 reviews so far
42%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle

Have you used Zetia (ezetimibe)?

Leave a review
Side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
12possible side effects
  • Diarrhea
    4%
  • Common cold
    4%
  • Sore throat
    4%
  • Sinus infection
    3%
  • Joint pain
    3%
  • Pain in arms and legs
    3%
  • Muscle pain
    3%
  • Abnormal liver tests
    3%
  • Fatigue
    2%
  • Flu
    2%
  • Back pain
    2%
  • Gallbladder removal
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings
  • Harm to fetus
  • Muscle pain
    • Taking Zetia (ezetimibe) with statins
  • Abnormal liver blood tests
    • Past history of liver disease
    • Taking Zetia (ezetimibe) with statins
See more detailed risks and warnings