Compare Tums vs. Pepcid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tums
(calcium carbonate)

Pepcid
(famotidine)

Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
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Best available price for 60 (20mg) tablets of famotidine
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.22Tums
Reviews for Tums
82%
of people (All ages) say Tums is worth it
43%
say it works well
5%
say it's a big hassle
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Reviews for Pepcid
75%
+7% better vs. Tums
41%
+2% better vs. Tums
8%
+3% better vs. Tums
853 reviews
Have you used Pepcid (famotidine)?
Worth itNot sureNot worth it
Side effects
TumsPepcid

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »
  • Headache 5%
  • Diarrhea 2%
More Pepcid side effects »
How it works
TumsPepcid
Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.
Type of medication
TumsPepcid
Over-the-counterPrescription or OTC
Available as
TumsPepcid
  • Chewable tablet
  • Liquid
  • Pill
  • Chewable tablet
  • Liquid
Used for
TumsPepcid
Risk factors for serious side effects
TumsPepcid
    Coming soon.
    • Current kidney disease
    Detailed Pepcid (famotidine) risks & warnings »
    Pregnancy

    Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

    Interactions
    TumsPepcid
    No interactions related info.
    • Few drug interactions.
    Kidneys and liver
    TumsPepcid
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    Upsides and benefits
    TumsPepcid
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    • Most people can take Famotidine without any noticeable day-to-day side effects.
    • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • Available as both a generic and over-the-counter option, so it's pretty affordable.
    • Few drug interactions.
    Downsides and risks
    TumsPepcid
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
    • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
    • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
    Tips from our pharmacists for people taking the medication
    TumsPepcid
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    • Short-term treatment of ulcers and acid reflux.
    Learn more
    More about TumsSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tums (calcium carbonate)?
    Worth itNot sureNot worth it
    More about PepcidSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Pepcid (famotidine)?
    Worth itNot sureNot worth it