Compare Tums vs. Pepcid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tums
(Calcium Carbonate)

Pepcid
(Famotidine)

Relieves heartburn. Tums (Calcium Carbonate) gives quick relief for heartburn, but don't expect it to last all day.Relieves heartburn. Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
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Reviews & ratings
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5.21970802919708Tums
Reviews for Tums (Calcium Carbonate)
82%
of people (All ages) say Tums (Calcium Carbonate) is worth it
43%
say it works well
5%
say it's a big hassle
1370 reviews
Have you used Tums (Calcium Carbonate)?
Worth itNot sureNot worth it
Reviews for Pepcid (Famotidine)
75%
7% vs. Tums (Calcium Carbonate)
41%
2% vs. Tums (Calcium Carbonate)
8%
3% vs. Tums (Calcium Carbonate)
848 reviews
Have you used Pepcid (Famotidine)?
Worth itNot sureNot worth it
Side effects
TumsPepcid

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »

The Pepcid FDA package insert doesn’t have numbers about how common side effects are.

More about Pepcid side effects »
How it works
TumsPepcid
Tums (Calcium Carbonate) is an antacid. It counteracts the effects of stomach acid to relieve heartburn and acid tummy (indigestion).Pepcid (Famotidine) is a type of antacid called an H2 blocker. It blocks the chemical histamine, which lowers acid production in your stomach. This treats heartburn and helps ulcers heal.
Type of medication
TumsPepcid
AntacidOver-the-counter
Acid reducer
Histamine blocker
Prescription or OTC
Available as
TumsPepcid
  • Chewable tablet
  • Liquid
  • Pill
  • Chewable tablet
  • Liquid
Used for (click to learn more)
TumsPepcid
Risk factors for serious side effects
TumsPepcid
    • Current kidney disease
    • Kidney dialysis
    • Hyperparathyroid disease
    • Taking high doses of Vitamin D
    • Previous kidney stones
    Detailed Tums (Calcium Carbonate) risks & warnings »
      • Current kidney disease
        Detailed Pepcid (Famotidine) risks & warnings »
        Pregnancy

        The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

        Research studies with animals haven’t found a risk to unborn babies, but it hasn’t been properly studied in humans.

        Interactions
        TumsPepcid
        • You need to separate Tums from some medications to avoid interactions.
        • Few drug interactions.
        Kidneys and liver
        TumsPepcid
        • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
        • If you have kidney or hyperparathyroid disease Tums (Calcium Carbonate) can build up in your blood. This may can cause toxic levels of calcium in your body. This is more likely if you have severe kidney disease (defined as a kidney function blood test called GFR of less than 30ml/min). If you have severe kidney disease or are on kidney dialysis don't use Tums (Calcium Carbonate); a different antacid would be better for you.
        • Tums (Calcium Carbonate) contains calcium. Calcium can be an ingredient in some kidney stones. If you have had kidney stones in the past (especially the calcium-containing kind) be careful using Tums (Calcium Carbonate). Use the lowest dose for the shortest time possible or just play it safe and use a different antacid instead.
        • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
        • Because Pepcid (Famotidine) is processed by the kidney it can cause some worrisome side effects for people with kidney problems. These include confusion, delirium, and a dangerous irregular heartbeat known as QT prolongation. If you have kidney problems, you may need a different dose to prevent this increased risk for side effects.
        Upsides and benefits
        TumsPepcid
        • Works really fast.
        • Available over the counter without a prescription.
        • Cheap.
        • Most people can take Famotidine without any noticeable day-to-day side effects.
        • Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
        • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
        • Available as both a generic and over-the-counter option, so it's pretty affordable.
        • Few drug interactions.
        Downsides and risks
        TumsPepcid
        • Doesn't last very long.
        • Other antacids like Zantac (H2 blockers) and omeprazole (proton pump inhibitors) can work better and last longer.
        • Some chalky aftertaste.
        • Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
        • Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
        • Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
        Tips from our pharmacists for people taking the medication
        TumsPepcid
        • Take at the first sign of discomfort.
        • You might need to take more than once a day but pay attention to the instructions on your bottle to avoid overdosing.
        • You need to separate Tums from some medications to avoid interactions.
        • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
        • People with kidney disease on dialysis may need to take a lower dose or avoid use. Your doctor can do blood tests to see if it's safe to use.
        • Don't take if you have high blood calcium levels.
        • Short-term treatment of ulcers and acid reflux.
        Learn more
        More about TumsSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Tums (Calcium Carbonate)?
        Worth itNot sureNot worth it
        More about PepcidSide effectsReviews & ratingsAlternativesFDA package insert
        Have you used Pepcid (Famotidine)?
        Worth itNot sureNot worth it