Compare Tums vs. Zantac

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tums
(calcium carbonate)

Zantac 75
(ranitidine)

Relieves heartburn. Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.Relieves heartburn and stomach ulcers. Zantac 75 (ranitidine) is an effective and inexpensive medicine for hearburn with few side effects, but may interfere with other drugs.
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.22Tums
Reviews for Tums
82%
of people (All ages) say Tums is worth it
43%
say it works well
5%
say it's a big hassle
1373 reviews
Have you used Tums (calcium carbonate)?
Worth itNot sureNot worth it
Reviews for Zantac
72%
+10% better vs. Tums
44%
-1% worse vs. Tums
7%
+2% better vs. Tums
1062 reviews
Have you used Zantac 75 (ranitidine)?
Worth itNot sureNot worth it
Side effects
TumsZantac

We haven’t found good data for Tums side effects.

FDA side effect reports for Tums »

The Zantac FDA package insert doesn’t have numbers about how common side effects are.

More about Zantac side effects »
How it works
TumsZantac
Tums (Calcium carbonate) is an antacid. It relieves heartburn and indigestion by neutralizing stomach acid.Zantac 75 (ranitidine) reduces the production of acid by blocking a chemical from acting on the acid-producing cells in your stomach.
Type of medication
TumsZantac
Over-the-counterPrescription or OTC
Available as
TumsZantac
  • Chewable tablet
  • Liquid
  • Pill
  • Oral solution
  • Oral syrup
  • Injection
Used for
TumsZantac
Risk factors for serious side effects
TumsZantac
    Coming soon.
    • Aged 60 years or older
    • Kidney conditions
    • Liver conditions
    • Acute Porphyria
    • Asthma
    Detailed Zantac 75 (ranitidine) risks & warnings »
    Pregnancy
    Interactions
    TumsZantac
    No interactions related info.
    • Zantac 75 (ranitidine) can interact with certain prescription and over-the-counter medications. Let your doctor or pharmacist know about the medicines you are currently taking.
    Alcohol
    TumsZantac
    No alcohol related info.
    • The syrup product may contain up to 7.5% of alcohol.
    Kidneys and liver
    TumsZantac
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    No kidneys and liver related info.
    Upsides and benefits
    TumsZantac
    • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
    • Tums (Calcium carbonate) starts working in seconds.
    • Has minimal side effects.
    • Available in chewable form.
    • Is inexpensive and readily available over-the-counter.
    • Coupons are available – speak to your doctor or pharmacist.
    • Zantac 75 (ranitidine) works well to relieve heartburn symtoms and is quite tolerable.
    • You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
    • If you have trouble swallowing pills you may find the liquid product a good option.
    • Inexpensive with over-the-counter and generic options.
    • Coupons are available for the brand product - speak to your doctor or pharmacist.
    Downsides and risks
    TumsZantac
    • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
    • May increase calcium levels too much in people with kidney or thyroid conditions.
    • May have a chalky taste.
    • Zantac 75 (ranitidine) doesn't work as quickly as some other acid reducers. Speak to your doctor or pharmacist if you need quicker relief.
    • Zantac 75 (ranitidine) does not last as long as some other acid reducers. Speak to your doctor or pharmacist if you need longer relief.
    • May not be as effective in healing the esophagus when it is inflammed or torn, known as erosive esophagitis. Your doctor will assess which medication is best for you.
    • Can lower your vitamin B12 levels if you use Zantac 75 (ranitidine) for a long time. Your doctor can order lab tests to monitor your vitamin B12 levels.
    Tips from our pharmacists for people taking the medication
    TumsZantac
    • Take at the first sign of discomfort.
    • You may need to separate Tums (Calcium carbonate) from some medicines to avoid interactions. Talk to your doctor or pharmacist about all the medicines you're taking, including prescription, supplements, and over the counter medicines.
    • Eating smaller, more frequent meals can help alleviate some symptoms of heartburn.
    • Certain spicy or fatty foods increase your risk of heartburn. Talk to your doctor or pharmacist to find out which foods you should avoid.
    • Avoiding eating 3 hours before bedtime can also help prevent heartburn.
    • If heartburn doesn't improve or lasts more than 2 weeks, talk to your doctor.
    • To prevent a heartburn attack, take Zantac 75 (ranitidine) 30 minutes before eating.
    • Works within 30 to 60 minutes. Relief lasts up to 12 hours.
    • Do not use Zantac 75 (ranitidine) for more than 14 days. Talk to your doctor if your symptoms do not improve after 2 weeks of using the over-the-counter product, as this may indicate a more serious problem.
    • The syrup product may contain up to 7.5% of alcohol.
    • Speak to your doctor or pharmacist about lifestyle and dietary changes that can help prevent heartburn.
    Learn more
    More about TumsSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tums (calcium carbonate)?
    Worth itNot sureNot worth it
    More about ZantacSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Zantac 75 (ranitidine)?
    Worth itNot sureNot worth it