Compare Tylenol Sinus vs. Dimetapp Cold and Allergy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tylenol Sinus
(Acetaminophen / Phenylephrine)

Dimetapp Cold And Allergy
(Phenylephrine / Brompheniramine)

Relieves pain and congestion. Tylenol Sinus (Acetaminophen / Phenylephrine) is a good combination medicine to relieve pain and congestion. Be careful to not take too much acetaminophen (APAP) each day.Relieves congestion and allergy symptoms for kids. Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is good for multiple nasal symptoms, but it can make you really drowsy.
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Reviews & ratings
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4.9226190476190474Tylenol Sinus
Reviews for Tylenol Sinus (Acetaminophen / Phenylephrine)
74%
of people (All ages) say Tylenol Sinus (Acetaminophen / Phenylephrine) is worth it
31%
say it works well
5%
say it's a big hassle
1176 reviews
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Side effects
Tylenol SinusDimetapp Cold and Allergy

We haven’t found good data for Tylenol Sinus side effects.

FDA side effect reports for Tylenol Sinus »

We haven’t found good data for Dimetapp Cold and Allergy side effects.

FDA side effect reports for Dimetapp Cold and Allergy »
How it works
Tylenol SinusDimetapp Cold and Allergy
Tylenol Sinus (Acetaminophen / Phenylephrine) is a combination medicine that treats cold and allergy symptoms. Acetaminophen relieves pain and reduces fever. Phenylephrine is a decongestant that clears your sinuses.Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine that relieves allergy and cold symptoms. Brompheniramine (an antihistamine) prevents allergy symptoms like runny nose, sneezing, and itchy eyes or skin. Phenylephrine (a decongestant) clears your sinuses.
Type of medication
Tylenol SinusDimetapp Cold and Allergy
Pain reliever
APAP
DecongestantOver-the-counter
DecongestantAntihistamine
1st generation
Over-the-counter
Available as
Tylenol SinusDimetapp Cold and Allergy
  • Pill
  • Chewable tablet
  • Liquid
Used for (click to learn more)
Tylenol SinusDimetapp Cold and Allergy
Risk factors for serious side effects
Tylenol SinusDimetapp Cold and Allergy
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
  • History of high blood pressure
  • Taking MAO inhibitors
  • Women of childbearing age
Detailed Tylenol Sinus (Acetaminophen / Phenylephrine) risks & warnings »
  • Taking with alcohol
  • Taking with other medicines that make you less alert
  • Women of childbearing age
  • History of high blood pressure
  • Taking MAO inhibitors
  • Age 65 years or older
  • Glaucoma
  • Benign prostatic hypertrophy (BPH)
Detailed Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) risks & warnings »
Pregnancy category
Tylenol SinusDimetapp Cold and Allergy
Sleep
No specific sleep related info.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
Upsides and benefits
Tylenol SinusDimetapp Cold and Allergy
  • Tylenol Sinus (Acetaminophen / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a headache, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than to other pain medications like aspirin or ibuprofen.
  • Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine with a decongestant and an antihistamine that's helpful in treating nasal symptoms related to cold and allergy.
  • Brompheniramine (the antihistamine) is useful for itchy eyes, runny nose, or constant sneezing.
  • Phenylephrine (the decongestant) is good for relieving congestion.
Downsides and risks
Tylenol SinusDimetapp Cold and Allergy
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it is a very common ingredient in pain and cold/flu combination medicines.
  • If you don't really need both of the medications in this combination, you'd be taking extra medicine and might have extra side effects for no reason.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • Phenylephrine (the decongestant) doesn't last as long as other oral decongestants like pseudoephedrine, but can cause jitteriness.
  • The two medications in this medicine can somewhat work against each other, with one making you sleepy and the other making you jittery.
Tips from our pharmacists for people taking the medication
Tylenol SinusDimetapp Cold and Allergy
  • Starts working in 30 minutes.
  • Phenylephrine (the decongestant ingredient) can make you restless, so don't take it too close to bedtime.
  • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
  • Follow age-specific dosing instructions on how much to take.
  • Let your doctor know if your symptoms don't improve in a few days.
  • Only use the provided dosage cup to measure the medicine. Don't use a spoon.
  • Follow the age-specific dosing instructions on how much to take. Don't take more than what's recommended on the package.
  • Talk to a doctor if the symptoms don't get better in 1 week.
Learn more
More about Tylenol SinusSide effectsReviews & ratingsAlternativesFDA package insert
Have you used Tylenol Sinus (Acetaminophen / Phenylephrine)?
Worth itNot sureNot worth it
More about Dimetapp Cold and AllergySide effectsReviews & ratingsAlternativesFDA package insert
Have you used Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine)?
Worth itNot sureNot worth it