Compare Tylenol Sinus vs. Dimetapp Cold And Allergy

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves pain and congestion.

Tylenol Sinus (Acetaminophen / Phenylephrine) is a good combination medicine to relieve pain and congestion. Be careful to not take too much acetaminophen (APAP) each day.

3.6/ 5 average rating with 1176 reviewsforTylenol Sinus
Relieves congestion and allergy symptoms for kids.

Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is good for multiple nasal symptoms, but it can make you really drowsy.

3.4/ 5 average rating with 24 reviewsforDimetapp Cold And Allergy
Upsides
  • Tylenol Sinus (Acetaminophen / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a headache, and pain.
  • The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
  • The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than to other pain medications like aspirin or ibuprofen.
  • Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) is a combination medicine with a decongestant and an antihistamine that's helpful in treating nasal symptoms related to cold and allergy.
  • Brompheniramine (the antihistamine) is useful for itchy eyes, runny nose, or constant sneezing.
  • Phenylephrine (the decongestant) is good for relieving congestion.
Downsides
  • If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
  • Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
  • You shouldn't use it if you have high blood pressure.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it is a very common ingredient in pain and cold/flu combination medicines.
  • If you don't really need both of the medications in this combination, you'd be taking extra medicine and might have extra side effects for no reason.
  • Brompheniramine (the antihistamine) can cause dizziness, drowsiness, dry eyes/mouth, and constipation.
  • Phenylephrine (the decongestant) doesn't last as long as other oral decongestants like pseudoephedrine, but can cause jitteriness.
  • The two medications in this medicine can somewhat work against each other, with one making you sleepy and the other making you jittery.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Liquid
No pricing information available
No pricing information available
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Reviews
1176 reviews so far
74%
saidit'sworth it
31%
saiditworked well
5%
saidit'sa big hassle

Have you used Tylenol Sinus (Acetaminophen / Phenylephrine)?

Leave a review
24 reviews so far
58%
saidit'sworth it
29%
saiditworked well
8%
saidit'sa big hassle

Have you used Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine)?

Leave a review
Side effects
The Tylenol Sinus (Acetaminophen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
The Dimetapp Cold And Allergy (Phenylephrine / Brompheniramine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    • History of liver disease
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings
  • Driving impairment
    • Taking with alcohol
    • Taking with other medicines that make you less alert
  • Harm to fetus
    • Women of childbearing age
  • High blood pressure
    • History of high blood pressure
    • Taking MAO inhibitors
  • Antihistamine side effects
    • Age 65 years or older
    • Glaucoma
    • Benign prostatic hypertrophy (BPH)
See more detailed risks and warnings