Compare Tylenol vs. Lodine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Tylenol Regular Strength
(acetaminophen)

Lodine
(etodolac)

Relieves pain and fever. Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain well, but it doesn't lower inflammation and swelling.Coming soon.
Find lowest prices
Powered by GoodRxSave on your next prescription. Be sure you’re getting the lowest price for your medication, even if you have insurance.
Coupons for Tylenol
Best available price for 30 (325mg) tablets of acetaminophen
Coupons for Lodine
Best available price for 60 (300mg) capsules of etodolac
Reviews & ratings
Filter group. All currently selected
Filter group. All currently selected
5.01Tylenol
Reviews for Tylenol Regular Strength (acetaminophen)
77%
of people (All ages) say Tylenol Regular Strength (acetaminophen) is worth it
37%
say it works well
3%
say it's a big hassle
1002 reviews
Have you used Tylenol Regular Strength (acetaminophen)?
Worth itNot sureNot worth it
Reviews for Lodine (etodolac)
Not enough review data. Review it!
-47% worse vs. Tylenol Regular Strength (acetaminophen)
Not enough review data. Review it!
-17% worse vs. Tylenol Regular Strength (acetaminophen)
Not enough review data. Review it!
-7% worse vs. Tylenol Regular Strength (acetaminophen)
Have you used Lodine (etodolac)?
Worth itNot sureNot worth it
Side effects
TylenolLodine

We haven’t found good data for Tylenol side effects.

FDA side effect reports for Tylenol »

We haven’t found good data for Lodine side effects.

FDA side effect reports for Lodine »
How it works
TylenolLodine
Tylenol Regular Strength (Acetaminophen) reduces fever and relieves pain, but doesn't lower inflammation and swelling.Coming soon.
Type of medication
TylenolLodine
Over-the-counter
Available as
TylenolLodine
  • Pill
  • Extended release tablet
  • Chewable tablet
  • Dissolving tablet
  • Gelcap
  • Liquid
  • Suppository
  • Pill
  • Extended release
Used for
TylenolLodine
  • Juvenile Rheumatoid Arthritis Osteoarthritis Pain Rheumatoid Arthritis
Risk factors for serious side effects
TylenolLodine
  • Drinking more than 2 alcoholic beverages a day
  • Taking with other Tylenol-containing medicines
  • History of liver disease
Detailed Tylenol Regular Strength (acetaminophen) risks & warnings »
    Coming soon.
    Pregnancy

    The FDA hasn’t classified this medicine’s effects on unborn babies. Talk with your doctor about this medicine if you’re pregnant or planning on it.

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Alcohol
    TylenolLodine
    • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
    • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
    No alcohol related info.
    Kidneys and liver
    TylenolLodine
    • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    No kidneys and liver related info.
    Pain
    TylenolLodine
    • Works well to relieve pain and fevers.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    No pain related info.
    Upsides and benefits
    TylenolLodine
    • Works well to relieve pain and fevers.
    • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
    • Tylenol Regular Strength (Acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin, ibuprofen, and naproxen.
    • Doesn't cause kidney damage and is safe to use if you have heart problems or if you're pregnant.
    • Although not without side effects, it's been around for a long time and is generally safe for short-term use.
    Coming soon
    Downsides and risks
    TylenolLodine
    • Tylenol Regular Strength (Acetaminophen) doesn't treat pain as well as other medications like ibuprofen and naproxen.
    • Drinking alcohol while taking Tylenol Regular Strength (Acetaminophen) can damage your liver.
    • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it's a very common ingredient in pain and cold/flu combination medicines.
    • Heavy alcohol drinkers shouldn't use Tylenol Regular Strength (Acetaminophen) since it can cause serious liver damage.
    Coming soon
    Tips from our pharmacists for people taking the medication
    TylenolLodine
    • Starts working in one hour.
    • Contains acetaminophen, also known as Tylenol or APAP. Taking too much can cause liver failure and death. Don't take more than what's recommended on the package or with other Tylenol-containing products.
    • Follow age-specific dosing instructions on how much to take. Adults should never take more than 3,000 milligrams (mg) in a single day.
    • Let your doctor know if your symptoms don't improve in a few days.
    Coming soon
    Learn more
    More about TylenolSide effectsReviews & ratingsAlternativesFDA package insert
    Have you used Tylenol Regular Strength (acetaminophen)?
    Worth itNot sureNot worth it
    More about LodineSide effectsReviews & ratingsFDA package insert
    Have you used Lodine (etodolac)?
    Worth itNot sureNot worth it