Compare Tylenol vs. Norco

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Relieves pain and fever.

Tylenol Regular Strength (acetaminophen) effectively reduces fever and relieves pain, but it doesn't lower inflammation and swelling.

3.7/ 5 average rating with 1002 reviewsforTylenol
Treats moderate to moderately severe pain.

Norco (hydrocodone / acetaminophen) is a good option to treat pain when over-the-counter medicines haven't worked, but it can lead to dependence and tolerance if taken for a long time.

3.7/ 5 average rating with 1194 reviewsforNorco
Upsides
  • Works well to relieve pain and fevers.
  • Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
  • Tylenol Regular Strength (acetaminophen) causes less upset stomach, ulcers, bruising, and bleeding than other pain medications like aspirin and Advil.
  • Doesn't cause kidney damage and is also safe to use if you have heart problems or if you're pregnant.
  • Tylenol Regular Strength (acetaminophen) has been used for a long time and is generally safe for short-term use.
  • Norco (hydrocodone / acetaminophen) has two medicines to treat moderate to moderately severe pain. The combination is more effective than either drug alone.
  • Norco (hydrocodone / acetaminophen) is more potent than many over-the-counter options.
  • You can take this with or without food.
  • This medicine also comes as a liquid if you have trouble swallowing.
  • Norco (hydrocodone / acetaminophen) is available as a generic.
Downsides
  • Tylenol Regular Strength (acetaminophen) doesn't treat some kinds of pain as well as other medications like Advil.
  • Drinking alcohol while taking Tylenol Regular Strength (acetaminophen) can damage your liver.
  • To avoid hurting your liver, you need to keep track of the total amount of acetaminophen you are taking since it's a very common ingredient in pain and cold combination medicines.
  • Heavy alcohol drinkers and people with liver problems should avoid using Tylenol Regular Strength (acetaminophen) since it can cause serious liver damage.
  • Constipation, dizziness, drowsiness, and nausea can commonly occur.
  • Since Norco (hydrocodone / acetaminophen) is a controlled medication, it cannot be refilled or transferred to another pharmacy.
  • Long-term use can cause dependence and tolerance.
  • Too much Norco (hydrocodone / acetaminophen) can damage the liver.
  • Not effective in treating all kinds of pain.
Used for
  • Moderate to severe pain
Dosage forms
  • Pill
  • Chewable tablet
  • Dissolving tablet
  • Liquid
  • Suppository
  • Injection
  • Pill
  • Liquid
Price
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Reviews
1002 reviews so far
77%
saidit'sworth it
37%
saiditworked well
3%
saidit'sa big hassle

Have you used Tylenol Regular Strength (acetaminophen)?

Leave a review
1194 reviews so far
67%
saidit'sworth it
44%
saiditworked well
13%
saidit'sa big hassle

Have you used Norco (hydrocodone / acetaminophen)?

Leave a review
Side effects
The Tylenol Regular Strength (acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
The Norco (hydrocodone / acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Accidental overdose and death
    • Medication administering errors
    • Injection formulation
    • Exceeding the recommended maximum daily limits
  • Liver damage
    • Drinking more than 2 alcoholic beverages a day
    • Taking with other Tylenol-containing medicines
    • History of liver disease
See more detailed risks and warnings
  • Liver failure
    • Current liver disease
    • Taking Norco (hydrocodone / acetaminophen) with alcohol
    • Taking other medicines containing acetaminophen
  • Slowed breathing
    • Age 65 or greater
    • High dosages
    • History of lung problems
    • Taking other painkillers or sedatives
  • Severe allergic reactions
    • Taking more than the prescribed dose
    • Long-term use
    • History of substance abuse
    • Younger age
  • Tolerance, dependence, and addiction
    • Taking more than the prescribed dose
    • Long-term use
    • History of drug abuse
    • Younger age
  • Constipation
    • Age 65 or greater
    • Long-term use of opioids
    • Taking drugs that cause constipation
  • Confusion and drowsiness
    • Drinking alcohol
    • Age 65 years or older
See more detailed risks and warnings