Compare Unisom vs. Robitussin DM

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Treats allergy symptoms and helps you sleep.

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

3.3/ 5 average rating with 585 reviewsforUnisom
Breaks up mucus and relieves cough.

Robitussin Dm (Guaifenesin / Dextromethorphan) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. You have to take it more often than other guaifenesin products.

3.7/ 5 average rating with 724 reviewsforRobitussin DM
Upsides
  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
  • Robitussin Dm (Guaifenesin / Dextromethorphan) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up and causes productive, wet coughs.
Downsides
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
  • Robitussin Dm (Guaifenesin / Dextromethorphan) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Robitussin Dm (Guaifenesin / Dextromethorphan)) stops you from coughing.
  • Needs to be taken more often during the day than other products with guaifenesin, like Mucinex.
  • Can cause sleepiness, dizziness, and an upset stomach.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Liquid
  • Liquid
No pricing information available
No pricing information available
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Reviews
585 reviews so far
58%
saidit'sworth it
32%
saiditworked well
11%
saidit'sa big hassle

Have you used Unisom Sleeptabs (Doxylamine)?

Leave a review
724 reviews so far
75%
saidit'sworth it
37%
saiditworked well
7%
saidit'sa big hassle

Have you used Robitussin Dm (Guaifenesin / Dextromethorphan)?

Leave a review
Side effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
The Robitussin Dm (Guaifenesin / Dextromethorphan) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Overdosage
    • Using other drugs with similar ingredients
  • Increased side effects
    • Age 65 years or older
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Hyperactivity
    • Children age 6 years or younger
  • Trouble urinating
    • Enlarged prostate
    • History of bladder problems
  • Vision changes
    • Glaucoma
  • Breastfeeding
    • Nursing mothers
See more detailed risks and warnings
  • Nausea and vomiting
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Cough warning
See more detailed risks and warnings