Compare Unisom vs. Rozerem

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Unisom Sleeptabs (Doxylamine)

Prescription or OTC

Rozerem (ramelteon)

Prescription only
Treats allergy symptoms and helps you sleep.

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

4.5/ 7 average rating with 585 reviewsforUnisom
Helps you fall asleep.

Rozerem (ramelteon) is a good sleep medicine that's not addictive, but it can be expensive.

Upsides
  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
  • Rozerem (ramelteon) isn't a controlled medicine, and it's safe to use in people age 65 or older.
  • If you stop taking Rozerem (ramelteon) suddenly, your insomnia won't come back.
  • Rozerem (ramelteon) won't make you feel hungover or groggy the next day.
Downsides
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
  • Rozerem (ramelteon) is only available as a brand name.
  • Rozerem (ramelteon) is only available in 1 strength.
  • If you take Rozerem (ramelteon) on a full stomach, it won't work as well.
  • Not recommended for children.
  • Rozerem (ramelteon) can't be used if you have sleep apnea.
Used for
Dosage forms
  • Pill
  • Chewable tablet
  • Liquid
  • Pill
Price
No pricing information available
Lowest price near you
$372.86
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Reviews
585 
58%
think this treatment is worth it
32%
think this treatment works well
11%
think this treatment is a hassle

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Side effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Dizziness
    4%
  • Sleepiness
    3%
  • Fatigue
    3%
  • Nausea
    3%
  • Worsening insomnia
    3%
See more detailed side effects
Risks and warnings
  • Overdosage

    Using other drugs with similar ingredients

  • Increased side effects

    Age 65 years or older

  • Driving impairment

    Taking with alcohol

    ...and 1 more risk factors

  • Hyperactivity

    Children age 6 years or younger

  • Trouble urinating

    Enlarged prostate

    ...and 1 more risk factors

  • Vision changes

    Glaucoma

  • Breastfeeding

    Nursing mothers

See more detailed risks and warnings
  • Breathing problems

    Alcohol

    ...and 1 more risk factors

See more detailed risks and warnings