Compare Vancocin vs. daptomycin

Head-to-head comparisons of medication uses, side effects, ratings, and more.



Coming soon.Treats bacterial infections. Cubicin (daptomycin) is an antibiotic that's usually only given in the hospital for serious infections. It can be given at home, but you will have to be taught how to inject it correctly.
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Coupons for Vancocin
Best available price for 40 (125mg) capsules of vancomycin
Coupons for daptomycin
Best available price for 14 (500mg) vials of daptomycin
Reviews & ratings
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Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Vancocin (vancomycin)?
Worth itNot sureNot worth it

Not enough reviews for this treatment. Help someone out, leave a review!

Have you used Cubicin (daptomycin)?
Worth itNot sureNot worth it
Side effects

We haven’t found good data for Vancocin side effects.

FDA side effect reports for Vancocin »
  • Diarrhea 5%
  • Headache 5%
  • Rash 4%
  • Abnormal liver tests 3%
  • Muscle damage 3%
  • Dizziness 2%
  • Urinary tract infection 2%
  • Low blood pressure 2%
  • Shortness of breath 2%
  • Sleep problems 9%
More daptomycin side effects »
How it works
Coming soon.Cubicin (daptomycin) is an antibacterial. It kills bacteria by preventing them from making their own DNA, RNA, and proteins they need to survive.
Type of medication
Prescription only
Available as
  • Pill
  • Injection
Used for
  • Clostridium Difficile Diarrhea Infection Of Skin AND OR Subcutaneous Tissue Infective Endocarditis Lower Respiratory Tract Infection Staphylococcal Enterocolitis Staphylococcal Infectious Disease
Risk factors for serious side effects
    Coming soon.
    • Allergy to antibiotics
    • History of kidney problems
    • Taking statins to lower cholesterol
    • Taking Cubicin (daptomycin) for at least 2 to 4 weeks
    Detailed Cubicin (daptomycin) risks & warnings »

    Research studies with animals found harmful effects on unborn babies. It hasn’t been properly studied in humans. The benefits might outweigh the risks even if you’re pregnant. Talk with your doctor.

    Upsides and benefits
    Coming soon
    • Cubicin (daptomycin) is good at treating severe and complicated bacterial infections.
    • It is able to kill bacteria that have resistance to other antibiotics.
    • Most people who take Cubicin (daptomycin) have few side effects.
    • You usually only need to take it once a day.
    Downsides and risks
    Coming soon
    • Cubicin (daptomycin) is usually only given for extremely serious infections that haven't responded to other antibiotics.
    • Cubicin (daptomycin) can cause muscle aches and weakness, which can lead to kidney problems.
    • You might need to have more blood tests done while taking Cubicin (daptomycin).
    • Like most antibiotics, it is common to have diarrhea when taking this medicine.
    • While Cubicin (daptomycin) is generic, it is usually very expensive.
    Tips from our pharmacists for people taking the medication
    Coming soon
    • Tell your doctor or get medical help right away if you get a rash, itchy skin, trouble breathing, or swelling in your face or mouth.
    • Diarrhea is a common side effect that should go away when you stop the medication. Tell your doctor if it doesn't stop, or if you develop very watery or bloody stools.
    • If you're taking statin medicines to lower your cholesterol, don't take them until you're done with Cubicin (daptomycin).
    • If you're taking Cubicin (daptomycin) at home, your doctor will place a small tube into your skin and you'll be taught how to inject the medicine correctly. Store Cubicin (daptomycin) in the fridge, but take it out 30 minutes before you inject it, so it can warm to room temperature.
    Learn more
    More about VancocinSide effectsReviews & ratingsFDA package insert
    Have you used Vancocin (vancomycin)?
    Worth itNot sureNot worth it
    More about daptomycinSide effectsAlternativesFDA package insert
    Have you used Cubicin (daptomycin)?
    Worth itNot sureNot worth it